It is well known that the fibrinolytic system actively participates in inflammatory processes. To
investigate the role of the urokinase system in atopic allergy, we assessed circulating levels …

Local and systemic changes in hemostasis are associated with allergic diseases. Apart from
their well documented role in regulation of plasminogen activation, components of the …

Accumulating evidence has indicated that different immune and inflammatory processes
may be accompanied by up-regulation of the uPA/uPAR system. Moreover, it has been …

Urokinase plasminogen activator (uPA) and its inhibitor (PAI-1) have been associated with
asthma. The aim of this study was to evaluate concentration of uPA and PAI-1 in induced …

Rationale: Urokinase plasminogen activator (uPA) interacts with its receptor on inflammatory
and migrating cells to regulate extracellular matrix degradation, cell adhesion, and …

Rationale Genetic polymorphisms in the asthma susceptibility gene, urokinase plasminogen
activator receptor (u PAR/PLAUR) have been associated with lung function decline and u …

Urokinase plasminogen activator (uPA) and its inhibitor (PAI-1) are involved in tiisue
remodeling and repair processes associated with acute and chronic inflammation. The aim …

Background Soluble urokinase plasminogen activator receptor (suPAR) has emerged as a
novel biomarker for various inflammatory conditions and has been proposed to associate …

The evidence gathered has pointed to the fibrinolytic system, which apart from its major role
in hemostasis may also be involved in inflammatory and immune processes. To understand …

METHODS: Baseline airway reactivity was measured as methacholine PC20. Following
segmental allergen challenge, cells were isolated from bronchoalveolar lavage (BAL) fluid …