Background: A new set of hybrid conjugates derived from 2-(4-isobutylphenyl) propanoic
acid (ibuprofen) is synthesized to overcome the drawbacks of the current non-steroidal anti …

New sets of ibuprofen and indomethacin conjugates comprising triazolyl heterocycle were
synthesized via click chemistry, adopting an optimized protocol through the molecular …

For reducing the gastrointestinal toxicity associated with ibuprofen, its carboxylic group was
masked by synthesizing its amide conjugates with ethylenediamine and benzathine (4a, 4b …

This work was aimed at synthesising and characterising five new conjugates of aspirin with
aromatic amino acids and testing them in vitro as potential selective cyclooxygenase 2 (COX …

A new set of ibuprofen-quinoline conjugates comprising quinolinyl heterocycle and
ibuprofen moieties linked by an alkyl chain were synthesized in good yields utilizing an …

A set of ester and amide derivatives of some acidic NSAIDs, including ibuprofen, ketoprofen,
and mefenamic acid (1-3), were synthesized and evaluated for their in vivo analgesic and …

Rationally designed conjugates of chrysin, indole, and barbituric acid were synthesized and
screened for their antiinflammatory activities through in vitro and in vivo experiments …

Ibuprofen–polyethylene glycol (PEG) conjugates (PEG-Ibu) were prepared and their
potential as a prolonged release system was investigated. Two PEG-Ibu conjugates were …

The synthesis of derivatives of three nonspecific COX-1 and COX-2 inhibitors, ibuprofen,
ketoprofen, naproxen is presented. These acids were connected via an amide bond with an …

Convenient Synthesis of Ibuprofen and Naproxen Aminoacyl, Dipeptidoyl and Ester Derivatives -
Katritzky - 2009 - Chemical Biology & Drug Design - Wiley Online Library Skip to Article Content …