Development of CRISPR-Cas systems for genome editing and beyond

F Zhang - Quarterly Reviews of Biophysics, 2019 - cambridge.org
The development of clustered regularly interspaced short-palindromic repeat (CRISPR)-Cas
systems for genome editing has transformed the way life science research is conducted and …

Recent progress in CRISPR/Cas9 technology

Y Mei, Y Wang, H Chen, ZS Sun, XD Ju - Journal of Genetics and …, 2016 - Elsevier
The clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 system, a
simple and efficient tool for genome editing, has experienced rapid progress in its …

Wide horizons of CRISPR-Cas-derived technologies for basic biology, agriculture, and medicine

KA Molla, S Karmakar, MT Islam - CRISPR-Cas methods, 2020 - Springer
The discovery and subsequent repurposing of the CRISPR (clustered regularly interspaced
short palindromic repeats) and Cas proteins (CRISPR-associated proteins) has …

CRISPR-Cas systems for editing, regulating and targeting genomes

JD Sander, JK Joung - Nature biotechnology, 2014 - nature.com
Targeted genome editing using engineered nucleases has rapidly gone from being a niche
technology to a mainstream method used by many biological researchers. This widespread …

Potential pitfalls of CRISPR/Cas9‐mediated genome editing

R Peng, G Lin, J Li - The FEBS journal, 2016 - Wiley Online Library
Recently, a novel technique named the clustered regularly interspaced short palindromic
repeat (CRISPR)/CRISPR‐associated protein (Cas) 9 system has been rapidly developed …

[HTML][HTML] CRISPR-Cas systems for genome editing, regulation and targeting

JD Sander, JK Joung - Nature biotechnology, 2014 - ncbi.nlm.nih.gov
Targeted genome editing using engineered nucleases has rapidly transformed from a niche
technology to a mainstream method used by many biological researchers. This widespread …

Delivery and specificity of CRISPR/Cas9 genome editing technologies for human gene therapy

JL Gori, PD Hsu, ML Maeder, S Shen… - Human gene …, 2015 - liebertpub.com
Genome editing using the clustered regularly interspaced short palindromic repeats
(CRISPR)/CRISPR associated 9 (Cas9) technology is revolutionizing the study of gene …

CRISPR/Cas9 for genome editing: progress, implications and challenges

F Zhang, Y Wen, X Guo - Human molecular genetics, 2014 - academic.oup.com
Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated
(Cas) protein 9 system provides a robust and multiplexable genome editing tool, enabling …

Beyond native Cas9: manipulating genomic information and function

H Mitsunobu, J Teramoto, K Nishida, A Kondo - Trends in biotechnology, 2017 - cell.com
Clustered regularly interspaced short palindromic repeats (CRISPR)-mediated manipulation
of genomic information is becoming more versatile by combining nuclease-deficient …

CRISPR/Cas9 in genome editing and beyond

H Wang, M La Russa, LS Qi - Annual review of biochemistry, 2016 - annualreviews.org
The Cas9 protein (CRISPR-associated protein 9), derived from type II CRISPR (clustered
regularly interspaced short palindromic repeats) bacterial immune systems, is emerging as a …