Allicin, an antioxidant and neuroprotective agent, ameliorates cognitive impairment

MS Nadeem, I Kazmi, I Ullah, K Muhammad, F Anwar - Antioxidants, 2021 - mdpi.com
Allicin (diallylthiosulfinate) is a defense molecule produced by cellular contents of garlic
(Allium sativum L.). On tissue damage, the non-proteinogenic amino acid alliin (S …

Allicin ameliorates cognitive deficits ageing-induced learning and memory deficits through enhancing of Nrf2 antioxidant signaling pathways

XH Li, CY Li, JM Lu, RB Tian, J Wei - Neuroscience letters, 2012 - Elsevier
Numerous studies have demonstrated that learning and memory abilities in the course of
normal aging cognitive abilities tend to decline and Nrf2 expression appears to decline with …

Neuroprotective effect of allicin against traumatic brain injury via Akt/endothelial nitric oxide synthase pathway-mediated anti-inflammatory and anti-oxidative activities

W Chen, J Qi, F Feng, G Bao, T Wang, M Xiang… - Neurochemistry …, 2014 - Elsevier
Allicin, one of the main biologically active compounds derived from garlic, has been shown
to exert various anti-oxidative and anti-inflammatory activities in in vitro and in vivo studies …

Allicin pharmacology: Common molecular mechanisms against neuroinflammation and cardiovascular diseases

FJM Marón, AB Camargo, W Manucha - Life sciences, 2020 - Elsevier
According to investigations in phytomedicine and ethnopharmacology, the therapeutic
properties of garlic (Allium sativum) have been described by ancestral cultures …

Allicin ameliorates aluminium- and copper-induced cognitive dysfunction in Wistar rats: relevance to neuro-inflammation, neurotransmitters and Aβ(1–42) analysis

S Kaur, K Raj, YK Gupta, S Singh - JBIC Journal of Biological Inorganic …, 2021 - Springer
Alzheimer's disease (AD) is a multifactorial neurological disorder associated with
neuropathological and neurobehavioral changes, like cognition and memory loss …

Allicin and other functional active components in garlic: Health benefits and bioavailability

MS Rahman - International Journal of Food Properties, 2007 - Taylor & Francis
Traditionally, the medical properties of garlic were recognized as early as 3000 BC. The
functional benefits of garlic are its antimicrobial activity, anticancer activity, antioxidant …

Bioavailability, health benefits, and delivery systems of allicin: a review

Y Deng, CT Ho, Y Lan, J Xiao, M Lu - Journal of agricultural and …, 2023 - ACS Publications
Garlic has been used worldwide as a spice due to its pungent taste and flavor-enhancing
properties. As a main biologically active component of the freshly crushed garlic extracts …

[HTML][HTML] The human allicin-proteome: S-thioallylation of proteins by the garlic defence substance allicin and its biological effects

MCH Gruhlke, H Antelmann, J Bernhardt… - Free Radical Biology …, 2019 - Elsevier
A single clove of edible garlic (Allium sativum L.) of about 10 g produces up to 5 mg of allicin
(diallylthiosulfinate), a thiol-reactive sulfur-containing defence substance that gives injured …

The effects of allicin, a reactive sulfur species from garlic, on a selection of mammalian cell lines

MCH Gruhlke, C Nicco, F Batteux, AJ Slusarenko - Antioxidants, 2016 - mdpi.com
Garlic (Allium sativum L.) has been used as a spice and medicinal plant since ancient times.
Garlic produces the thiol-reactive defence substance, allicin, upon wounding. The effects of …

Therapeutic potential of allicin and aged garlic extract in Alzheimer's disease

P Tedeschi, M Nigro, A Travagli, M Catani… - International Journal of …, 2022 - mdpi.com
Garlic, Allium sativum, has long been utilized for a number of medicinal purposes around the
world, and its medical benefits have been well documented. The health benefits of garlic …