Malaria, a parasite vector-borne disease, is one of the biggest health threats in tropical
regions, despite the availability of malaria chemoprophylaxis. The emergence and rapid …

Malaria, a parasite vector-borne disease, is one of the most significant health threats in
tropical regions, despite the availability of individual chemoprophylaxis. Malaria …

The emergence and rapid extension of Plasmodium falciparum resistance to various
antimalarial compounds has gradually limited malaria therapeutic possibilities available to …

New drugs are needed for preventing drug-resistant Plasmodium falciparum malaria. The
prophylactic efficacy of azithromycin against P. falciparum in malaria-immune Kenyans was …

Initial field malaria prophylaxis trials with azithromycin revealed insufficient efficacy against
falciparum malaria to develop azithromycin as a single agent. The objective of this in vitro …

Malaria, a parasite vector-borne disease, is one of the greatest health threats in tropical
regions, despite the availability of malaria chemoprophylaxis. The emergence and rapid …

The antimicrobial spectrum of azithromycin and clarithromycin suggests a number of further
uses for these newer macrolides. Favorable clinical and bacteriologic responses have been …

Azithromycin, the most potent antimalarial macrolide antibiotic, is synergistic with quinine
against Plasmodium falciparum in vitro. We assessed combinations of azithromycin and …

Azithromycin, an azalide analog of erythromycin was assayed for its in vitro activity against
multidrug-resistant Plasmodium falciparum K1 strain by measuring the 3H-hypoxanthine …

Background Malaria invasion of red blood cells involves multiple parasite-specific targets
that are easily accessible to inhibitory compounds, making it an attractive target for …