Orchestration of a blood-derived and ADARB1-centred network in Alzheimer's and Parkinson's disease

Z Song, Q Ding, Y Yang - Cellular Signalling, 2023 - Elsevier
The peripheral immune system is thought to influence the pathogenesis of the central
nervous system in Alzheimer's disease (AD) and Parkinson's disease (PD). This study aimed …

Integrated transcriptomics reveals the brain and blood biomarkers in Alzheimer's disease

H Yu, F Wang, J Wu, J Gong, S Bi… - CNS Neuroscience …, 2023 - Wiley Online Library
Background The systematic molecular associations between the peripheral blood cells and
brain in Alzheimer's disease (AD) remains unclear, which hinders our understanding of AD …

[HTML][HTML] Cellular transcriptional alterations of peripheral blood in Alzheimer's disease

L Song, YT Yang, Q Guo, ZIB Consortium, XM Zhao - BMC medicine, 2022 - Springer
Background Alzheimer's disease (AD), a progressive neurodegenerative disease, is the
most common cause of dementia worldwide. Accumulating data support the contributions of …

A systematic review of updated mechanistic insights towards Alzheimer's disease

A Mittal, R Sharma, S Sardana… - CNS & Neurological …, 2023 - ingentaconnect.com
Background: Alzheimer's disease (AD) is a degenerative neurological disorder that impairs
memory, cognitive abilities, and the ability to do everyday activities. This neurodegenerative …

Identification of common molecular biomarker signatures in blood and brain of Alzheimer's disease

MR Rahman, T Islam, M Shahjaman, JMW Quinn… - BioRxiv, 2018 - biorxiv.org
Background Alzheimers disease (AD) is a progressive neurodegenerative disease
characterized by memory loss and confusion. Neuroimaging and cerebrospinal fluid-based …

[HTML][HTML] Integrated analysis of miRNA and mRNA expression in the blood of patients with Alzheimer's disease

Z Wang, L Shen, Y Wang… - Molecular Medicine …, 2020 - spandidos-publications.com
Alzheimer's disease (AD) is a progressive neurodegenerative disease, which is considered
the most common type of dementia worldwide. The aim of the present study was to identify …

[HTML][HTML] Exploring the common pathogenesis of Alzheimer's disease and type 2 diabetes mellitus via microarray data analysis

X Ye, M Liu, X Wang, S Cheng, C Li, Y Bai… - Frontiers in Aging …, 2023 - frontiersin.org
Background Alzheimer's Disease (AD) and Type 2 Diabetes Mellitus (DM) have an
increased incidence in modern society. Although more and more evidence has supported …

[HTML][HTML] Integrating peripheral blood and brain transcriptomics to identify immunological features associated with Alzheimer's disease in mild cognitive impairment …

X Qian, X Liu, S Chen, H Tang - Frontiers in Immunology, 2022 - frontiersin.org
Background Immune system dysfunction has been proven to be an important pathological
event in Alzheimer's disease (AD). Mild cognitive impairment (MCI), as a transitional stage …

[HTML][HTML] Exercise modifies the transcriptional regulatory features of monocytes in alzheimer's patients: A multi-omics integration analysis based on single cell …

Y Chen, Y Sun, Z Luo, X Chen, Y Wang, B Qi… - Frontiers in Aging …, 2022 - frontiersin.org
Monocytes have been reported to be important mediators of the protective effect of exercise
against the development of Alzheimer's disease (AD). This study aims explored the …

An integrated approach to unravel a putative crosstalk network in Alzheimer's disease and Parkinson's disease

I Bisht, RK Ambasta, P Kumar - Neuropeptides, 2020 - Elsevier
Integration of multiple profiling data and construction of functional regulatory networks
provide a powerful approach to uncover functional relationships and significant molecular …