Prognostic value of an RNA expression signature derived from cell cycle proliferation genes in patients with prostate cancer: a retrospective study
Background Optimum management of clinically localised prostate cancer presents unique
challenges because of the highly variable and often indolent natural history of the disease …
challenges because of the highly variable and often indolent natural history of the disease …
Validation of an RNA cell cycle progression score for predicting death from prostate cancer in a conservatively managed needle biopsy cohort
Background: The natural history of prostate cancer is highly variable and difficult to predict
accurately. Better markers are needed to guide management and avoid unnecessary …
accurately. Better markers are needed to guide management and avoid unnecessary …
Prognostic value of a cell cycle progression signature for prostate cancer death in a conservatively managed needle biopsy cohort
Background: The natural history of prostate cancer is highly variable and it is difficult to
predict. We showed previously that a cell cycle progression (CCP) score was a robust …
predict. We showed previously that a cell cycle progression (CCP) score was a robust …
Validation of a cell-cycle progression gene panel to improve risk stratification in a contemporary prostatectomy cohort
MR Cooperberg, JP Simko, JE Cowan… - Journal of Clinical …, 2013 - escholarship.org
PurposeWe aimed to validate a previously described genetic risk score, denoted the cell-
cycle progression (CCP) score, in predicting contemporary radical prostatectomy (RP) …
cycle progression (CCP) score, in predicting contemporary radical prostatectomy (RP) …
Tumour genomic and microenvironmental heterogeneity for integrated prediction of 5-year biochemical recurrence of prostate cancer: a retrospective cohort study
Background Clinical prognostic groupings for localised prostate cancers are imprecise, with
30–50% of patients recurring after image-guided radiotherapy or radical prostatectomy. We …
30–50% of patients recurring after image-guided radiotherapy or radical prostatectomy. We …
Analytic and clinical validation of a prostate cancer–enhanced messenger RNA detection assay in whole blood as a prognostic biomarker for survival
Background Biomarkers based on detecting prostate cancer (PCa)-specific transcripts in
blood are associated with inferior outcomes, but their validation in a clinical context is …
blood are associated with inferior outcomes, but their validation in a clinical context is …
Prognostic utility of cell cycle progression score in men with prostate cancer after primary external beam radiation therapy
SJ Freedland, L Gerber, J Reid, W Welbourn… - International Journal of …, 2013 - Elsevier
Purpose To evaluate the prognostic utility of the cell cycle progression (CCP) score, a RNA
signature based on the average expression level of 31 CCP genes, for predicting …
signature based on the average expression level of 31 CCP genes, for predicting …
RNA biomarkers associated with metastatic progression in prostate cancer: a multi-institutional high-throughput analysis of SChLAP1
Background Improved clinical predictors for disease progression are needed for localised
prostate cancer, since only a subset of patients develop recurrent or refractory disease after …
prostate cancer, since only a subset of patients develop recurrent or refractory disease after …
Molecular sampling of prostate cancer: a dilemma for predicting disease progression
Background Current prostate cancer prognostic models are based on pre-treatment prostate
specific antigen (PSA) levels, biopsy Gleason score, and clinical staging but in practice are …
specific antigen (PSA) levels, biopsy Gleason score, and clinical staging but in practice are …
Prognostic value of blood mRNA expression signatures in castration-resistant prostate cancer: a prospective, two-stage study
D Olmos, D Brewer, J Clark, DC Danila… - The lancet …, 2012 - thelancet.com
Background Biomarkers are urgently needed to dissect the heterogeneity of prostate cancer
between patients to improve treatment and accelerate drug development. We analysed …
between patients to improve treatment and accelerate drug development. We analysed …
相关搜索
- prognostic value prostate cancer
- whole blood prostate cancer
- rna biomarkers prostate cancer
- prostatectomy cohort cell cycle
- biochemical recurrence prostate cancer
- clinical validation prostate cancer
- disease progression prostate cancer
- integrated prediction prostate cancer
- risk stratification cell cycle
- molecular sampling prostate cancer
- radiation therapy prostate cancer
- prognostic utility prostate cancer
- prognostic biomarker prostate cancer
- metastatic progression prostate cancer