A multitude of roles for the endogenous cannabinoid system has been proposed by recent
research efforts. A large number of endogenous cannabinoid neurotransmitters or …

Increasing interest in the biology, chemistry, pharmacology, and toxicology of cannabinoids
and in the development of cannabinoid medications necessitates an understanding of …

Abstract Δ 9-Tetrahydrocannabinol (THC) is the main source of the pharmacological effects
caused by the consumption of cannabis, both the marijuana-like action and the medicinal …

Cannabis is one of the most widely used drugs throughout the world. The psychoactive
constituent of cannabis, δ9‐tetrahydrocannabinol (δ9‐THC), produces a myriad of …

Mammalian tissues contain at least two types of cannabinoid receptor, CB 1, found mainly
on neurones and CB 2, found mainly in immune cells. Endogenous ligands for these …

For thousands of years, physicians and their patients employed cannabis as a therapeutic
agent. Despite this extensive historical usage, in the Western world, cannabis fell into …

Research into the pharmacology of individual cannabinoids that began in the 1940s, several
decades after the presence of a cannabinoid was first detected in cannabis, is concisely …

The endocannabinoids are lipid messengers that engage the same cell surface receptors
targeted by delta9-tetrahydrocannabinol, the active component of marijuana. They are …

Cannabis has been known as a medicine for several thousand years across many cultures.
It reached a position of prominence within Western medicine in the nineteenth century but …

Cannabis sativa has been known, used, and misused by mankind for centuries, and yet only
over the last two decades has research stemming from the chemical constituents specific to …