Matrix metalloproteinases and their inhibitors in pulmonary fibrosis: EMMPRIN/CD147 comes into play
L Chuliá-Peris, C Carreres-Rey, M Gabasa… - International journal of …, 2022 - mdpi.com
Pulmonary fibrosis (PF) is characterized by aberrant extracellular matrix (ECM) deposition,
activation of fibroblasts to myofibroblasts and parenchymal disorganization, which have an …
activation of fibroblasts to myofibroblasts and parenchymal disorganization, which have an …
Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) promotes lung fibroblast proliferation, survival and differentiation to myofibroblasts
NA Hasaneen, J Cao, A Pulkoski-Gross, S Zucker… - Respiratory …, 2016 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is a chronic progressively fatal disease.
Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) is a glycosylated transmembrane …
Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) is a glycosylated transmembrane …
Role of CD147 (EMMPRIN/Basigin) in tissue remodeling
D Guindolet, EE Gabison - The Anatomical Record, 2020 - Wiley Online Library
ABSTRACT CD147, also known as extracellular matrix metalloproteinase inducer
(EMMPRIN) or basigin, is expressed in a variety of cell types. It is involved in the regulation …
(EMMPRIN) or basigin, is expressed in a variety of cell types. It is involved in the regulation …
Matrix metalloproteinases as therapeutic targets for idiopathic pulmonary fibrosis
VJ Craig, L Zhang, JS Hagood… - American journal of …, 2015 - atsjournals.org
Idiopathic pulmonary fibrosis (IPF) is a restrictive lung disease that is associated with high
morbidity and mortality. Current medical therapies are not fully effective at limiting mortality …
morbidity and mortality. Current medical therapies are not fully effective at limiting mortality …
Role of matrix metalloproteinases in the pathogenesis of idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a progressive and devastating lung disorder of
unknown origin, with very poor prognosis and no effective treatment. The disease is …
unknown origin, with very poor prognosis and no effective treatment. The disease is …
Matrix metalloproteinase: An upcoming therapeutic approach for idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a debilitating condition where excess collagen
deposition occurs in the extracellular matrix. At first sight, it is expected that the level of …
deposition occurs in the extracellular matrix. At first sight, it is expected that the level of …
Pivotal role of matrix metalloproteinase 13 in extracellular matrix turnover in idiopathic pulmonary fibrosis
T Nkyimbeng, C Ruppert, T Shiomi, B Dahal, G Lang… - PloS one, 2013 - journals.plos.org
Rationale Idiopathic pulmonary fibrosis (IPF) is a fatal disease characterized by excessive
deposition of extracellular matrix (ECM). Objectives We investigated the regulation of matrix …
deposition of extracellular matrix (ECM). Objectives We investigated the regulation of matrix …
Role of matrix metalloprotease-2 and MMP-9 in experimental lung fibrosis in mice
T Bormann, R Maus, J Stolper, M Tort Tarrés… - Respiratory …, 2022 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is a diffuse parenchymal lung disease
characterized by exuberant deposition of extracellular matrix (ECM) proteins in the lung …
characterized by exuberant deposition of extracellular matrix (ECM) proteins in the lung …
[HTML][HTML] Matrix metalloproteinase 3 is a mediator of pulmonary fibrosis
CM Yamashita, L Dolgonos, RL Zemans… - The American journal of …, 2011 - Elsevier
Idiopathic pulmonary fibrosis (IPF) may be triggered by epithelial injury that results in
aberrant production of growth factors, cytokines, and proteinases, leading to proliferation of …
aberrant production of growth factors, cytokines, and proteinases, leading to proliferation of …
Role of matrix metaloproteases in idiopathic pulmonary fibrosis
Lung fibrosis is the final common pathway of a large variety of chronic lung disorders,
named interstitial lung diseases. The most aggressive form is the idiopathic pulmonary …
named interstitial lung diseases. The most aggressive form is the idiopathic pulmonary …