[HTML][HTML] Current understanding of hexavalent chromium [Cr (VI)] neurotoxicity and new perspectives

JP Wise Jr, JL Young, J Cai, L Cai - Environment international, 2022 - Elsevier
Abstract Hexavalent chromium [Cr (VI)] is a global environmental pollutant that increases
risk for several types of cancers and is increasingly being recognized as a neurotoxicant …

[HTML][HTML] Chromium induced neurotoxicity by altering metabolism in zebrafish larvae

Y Xu, L Wang, J Zhu, P Jiang, Z Zhang, L Li… - … and Environmental Safety, 2021 - Elsevier
Background Recently, both trivalent chromium Cr (III) and hexavalent chromium Cr (VI) have
been reported to produce neurotoxicity. However, the underlying mechanisms of the …

Mechanisms of chromium-induced toxicity

TL DesMarias, M Costa - Current opinion in toxicology, 2019 - Elsevier
Chromium is a pervasive environmental contaminant that is of great importance because of
its toxicity. Hexavalent chromium is a classified group 1 carcinogen with multiple complex …

[HTML][HTML] Oral chromium exposure and toxicity

H Sun, J Brocato, M Costa - Current environmental health reports, 2015 - Springer
Abstract Hexavalent chromium [Cr (VI)] is a known carcinogen when inhaled. However,
inhalational exposure to Cr (VI) affects only a small portion of the population, mainly by …

Carcinogenicity of chromium and chemoprevention: a brief update

Y Wang, H Su, Y Gu, X Song, J Zhao - OncoTargets and therapy, 2017 - Taylor & Francis
Chromium has two main valence states: hexavalent chromium (Cr [VI]) and trivalent
chromium (Cr [III]). Cr (VI), a well-established human carcinogen, can enter cells by way of a …

A comprehensive review on human health effects of chromium: Insights on induced toxicity

H Hossini, B Shafie, AD Niri, M Nazari… - … Science and Pollution …, 2022 - Springer
The growing use of heavy metals in most industrial activities has led to it being considered
as the most important environmental pollutant that may cause harm and toxicity to animals …

Toxicity and carcinogenicity of Cr (VI) in animal models and humans

M Costa - Critical reviews in toxicology, 1997 - Taylor & Francis
The toxicity and carcinogenicity of hexavalent chromium (Cr) in animal and human models
are reviewed. The focus of this review is not on the well-established fact that hexavalent Cr …

Chromium genotoxicity: A double-edged sword

KP Nickens, SR Patierno, S Ceryak - Chemico-biological interactions, 2010 - Elsevier
Certain forms of hexavalent chromium [Cr (VI)] are known respiratory carcinogens that
induce a broad spectrum of DNA damage. Cr (VI)-carcinogenesis may be initiated or …

Hexavalent chromium is carcinogenic to F344/N rats and B6C3F1 mice after chronic oral exposure

MD Stout, RA Herbert, GE Kissling… - Environmental …, 2009 - ehp.niehs.nih.gov
Background Hexavalent chromium [Cr (VI)] is a human carcinogen after inhalation exposure.
Humans also ingest Cr (VI) from contaminated drinking water and soil; however, limited data …

Carcinogenicity of hexavalent chromium

AL Holmes, SS Wise, JP Wise - Indian journal of medical research, 2008 - journals.lww.com
Abstract Hexavalent chromium (Cr (VI)), a commonly used industrial metal, is a well known
human lung carcinogen. Epidemiology and animal studies suggest that the particulate Cr …