Mimicking natural tissue structure is crucial for engineered tissues with intended
applications ranging from regenerative medicine to biorobotics. Native tissues are highly …

Tissue engineering creates biological tissues that aim to improve the function of diseased or
damaged tissues. To enhance the function of engineered tissues there is a need to generate …

The survival of vertebrate organisms depends on highly regulated delivery of oxygen and
nutrients through vascular networks that pervade nearly all tissues in the body …

One of the principal challenges facing the field of tissue engineering over the past 2
decades has been the requirement for large-scale engineered constructs comprising …

In vitro-generated tissues hold significant promise in modern biology since they can
potentially mimic physiological and pathological tissues. However, these are currently …

The vasculature is an essential component of the circulatory system that plays a vital role in
the development, homeostasis, and disease of various organs in the human body. The …

This review highlights recent trends towards the development of in vitro multicellular systems
with definite architectures, or “organs on chips”. First, the chemical composition and …

3D hydrogel microstructures that encapsulate cells have been used in broad applications in
microscale tissue engineering, personalized drug screening, and regenerative medicine …

Due to the complex structures of living systems, with size scales spanning from the micron to
millimeter range, the use of microtechnology to recreate in vivo-like architecture has exciting …

Functional and perfusable vascular network formation is critical to ensure the long-term
survival and functionality of engineered tissues after their transplantation. Although several …