Historically, lobular carcinoma in situ (LCIS) has been poorly understood in terms of its
biologic behavior and natural history. There is considerable debate as to whether LCIS …

Lobular carcinoma in situ (LCIS) of the breast typically is an incidental finding in breast
biopsies performed for a variety of reasons. As patients with LCIS have a bilaterally …

1593 Background: Increased breast cancer risk conferred by lobular carcinoma in situ
(LCIS) is poorly understood. Molecular studies suggest a subset of LCIS may behave as …

Lobular carcinoma in situ (LCIS) is not only a relative newcomer among breast lesions, but
in its short span of 50 years in has gradually evolved from a rare form of breast cancer to …

Lobular carcinoma in situ (LCIS) is a risk factor and a nonobligate precursor of breast
carcinoma. The relative risk of invasive carcinoma after classic LCIS diagnosis is …

Lobular carcinoma in situ (LCIS) exists as two main subtypes, classic and pleomorphic.
While it may sometimes be an invasive cancer precursor, LCIS can be treated as a risk …

Lobular carcinoma in situ (LCIS) has gone from a rare form of mammary cancer to a marker
of increased risk. Treatment options have undergone a corresponding change from …

Lobular carcinoma in situ (LCIS) of the breast is generally considered an indicator for a
bilaterally increased risk of invasive breast cancer (IBC). However, as recent studies …

Context.—Lobular carcinoma in situ (LCIS) refers to a neoplastic proliferation of cells that
characteristically shows loss of E-cadherin expression and has long been regarded as a risk …

Lobular carcinoma in situ (LCIS) is a noninvasive lesion of the breast considered to be a
nonobligate precursor of invasive lobular carcinoma 1. The pathologic definition is …