The high prevalence of obesity and associated metabolic disorders are one of the major
public health problems worldwide. Among the main causal factors of obesity, excessive …

Hypothalamic regulations of food intake are altered during obesity. The dopaminergic
mesocorticolimbic system, responsible for the hedonic response to food intake, is also …

Accumulating evidence suggests that high-fat diet (HFD) induced metabolic disorders are
associated with dysbiosis of gut microbiota. However, no study has explored the effect of …

The gut microbiota contributes to fat mass and the susceptibility to obesity. However, the
underlying mechanisms are not completely understood. To investigate whether the gut …

Methods: Wistar rats were fed four different diets (WD, CAF, HFD and a low-fat diet) for 18
weeks. Metabolic parameters and gut microbiota changes were then characterized. Results …

The gut microbiota is proposed as a “metabolic organ” involved in energy utilization and is
associated with obesity. Dietary intervention is one of the approaches for obesity …

Obesity can be caused by microbes producing metabolites; it is thus important to determine
the correlation between gut microbes and metabolites. This study aimed to identify gut …

The gut microbiota is emerging as a new factor in the development of obesity. Many studies
have described changes in microbiota composition in response to obesity and high fat diet …

Diet-induced obesity contributes to the development of type 2 diabetes, insulin resistance,
metabolic inflammation, oxidative and endoplasmic reticulum (ER) stress. Overall, obesity is …

Obesity is one of the major health issues in the United States. Consumption of diets rich in
energy, notably from fats and sugars (high-fat/high-sugar diet: HF/HSD) is linked to the …