Chronic intermittent hypoxia induces local inflammation of the rat carotid body via functional upregulation of proinflammatory cytokine pathways
SY Lam, Y Liu, KM Ng, CF Lau, EC Liong… - Histochemistry and cell …, 2012 - Springer
Maladaptive changes in the carotid body (CB) induced by chronic intermittent hypoxia (IH)
account for the pathogenesis of cardiovascular morbidity in patients with sleep-disordered …
account for the pathogenesis of cardiovascular morbidity in patients with sleep-disordered …
Chronic hypoxia upregulates the expression and function of proinflammatory cytokines in the rat carotid body
SY Lam, GL Tipoe, EC Liong, ML Fung - Histochemistry and cell biology, 2008 - Springer
The structure and function of the carotid body are greatly altered during chronic hypoxia.
Recent studies showed the expression of interleukin (IL)-1 receptor and IL-6 receptor in the …
Recent studies showed the expression of interleukin (IL)-1 receptor and IL-6 receptor in the …
Adaptation to chronic hypoxia involves immune cell invasion and increased expression of inflammatory cytokines in rat carotid body
X Liu, L He, L Stensaas, B Dinger… - American Journal of …, 2009 - journals.physiology.org
Exposure to chronic hypoxia (CH; 3–28 days at 380 Torr) induces adaptation in mammalian
carotid body such that following CH an acute hypoxic challenge elicits an abnormally large …
carotid body such that following CH an acute hypoxic challenge elicits an abnormally large …
Differential expression of pro-inflammatory cytokines, endothelin-1 and nitric oxide synthases in the rat carotid body exposed to intermittent hypoxia
The enhanced carotid body (CB) chemosensory response to hypoxia induced by chronic
intermittent hypoxia (CIH) has been attributed to oxidative stress, which is expected to …
intermittent hypoxia (CIH) has been attributed to oxidative stress, which is expected to …
Carotid body inflammation and cardiorespiratory alterations in intermittent hypoxia
Chronic intermittent hypoxia (CIH), a main feature of obstructive sleep apnoea (OSA),
increases hypoxic ventilatory responses and elicits hypertension, partially attributed to an …
increases hypoxic ventilatory responses and elicits hypertension, partially attributed to an …
Upregulation of a local renin–angiotensin system in the rat carotid body during chronic intermittent hypoxia
SY Lam, Y Liu, KM Ng, EC Liong… - Experimental …, 2014 - Wiley Online Library
New Findings• What is the central question of this study? Expression of the renin–
angiotensin system (RAS) may play a pathogenic role in the augmented activity of carotid …
angiotensin system (RAS) may play a pathogenic role in the augmented activity of carotid …
Chronic intermittent hypoxia-induced vascular enlargement and VEGF upregulation in the rat carotid body is not prevented by antioxidant treatment
RD Rio, C Muñoz, P Arias, FA Court… - … of Physiology-Lung …, 2011 - journals.physiology.org
Chronic intermittent hypoxia (CIH), a characteristic of sleep obstructive apnea, enhances
carotid body (CB) chemosensory responses to hypoxia, but its consequences on CB …
carotid body (CB) chemosensory responses to hypoxia, but its consequences on CB …
Reactive oxygen radicals and gaseous transmitters in carotid body activation by intermittent hypoxia
NR Prabhakar, YJ Peng, G Yuan, J Nanduri - Cell and tissue research, 2018 - Springer
Sleep apnea is a prevalent respiratory disease characterized by periodic cessation of
breathing during sleep causing intermittent hypoxia (IH). Sleep apnea patients and rodents …
breathing during sleep causing intermittent hypoxia (IH). Sleep apnea patients and rodents …
Carotid body and cardiorespiratory alterations in intermittent hypoxia: the oxidative link
Intermittent hypoxia, a feature of obstructive sleep apnoea, potentiates ventilatory hypoxic
responses, alters heart rate variability and produces hypertension, partially owing to an …
responses, alters heart rate variability and produces hypertension, partially owing to an …
Cellular mechanisms in intermittent hypoxia-induced cardiac damage in vivo
Q Han, SC Yeung, MSM Ip, JCW Mak - Journal of physiology and …, 2014 - Springer
Obstructive sleep apnea (OSA), characterized by intermittent hypoxia (IH) during sleep, is
increasingly recognized as an independent risk factor of cardiovascular diseases. OSA is …
increasingly recognized as an independent risk factor of cardiovascular diseases. OSA is …
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