The discovery of therapeutic miRNAs is one of the most exciting challenges for
pharmaceutical companies. Since the first miRNA was discovered in 1993, our knowledge of …

From chemotherapy and radiotherapy to molecular targeted therapy, in recent decades, we
have witnessed the acceleration of cancer treatments. However, nowadays, it has …

Simple Summary Cancer is a complex disease associated with deregulation of numerous
genes. In addition, redundant cellular pathways limit efficiency of monotarget drugs in …

Despite the recent progress in cancer management approaches, the mortality rate of cancer
is still growing and there are lots of challenges in the clinics in terms of novel therapeutics …

MicroRNAs (miRNAs) represent a new class of diagnostic and prognostic biomarker as well
as new therapeutic targets in cancer therapy. miRNAs are gaining significant interest due to …

Introduction: The results of cancer-associated miRNA research have yielded surprising
insights into the pathogenesis of a range of different cancers. Many of the dysregulated …

microRNAs (miRNAs) are small non‐coding RNAs that regulate gene expression post‐
transcriptionally by interfering with the translation of one or more target mRNAs. The unique …

Abstract MicroRNAs (miRNAs), small non-coding RNAs, can regulate post-transcriptional
gene expressions and silence a broad set of target genes. miRNAs, aberrantly expressed in …

Small noncoding RNAs, as post-translational regulators of many target genes, are not only
markers of neoplastic disease initiation and progression, but also markers of response to …

Simple Summary Over the last few years, we have witnessed incredible advancements in
anti-tumor drug development. microRNAs, a class of small non-coding RNAs dysregulated …