[HTML][HTML] Fast, accurate local ancestry inference with FLARE
Local ancestry is the source ancestry at each point in the genome of an admixed individual.
Inferred local ancestry is used for admixture mapping and population genetic analyses. We …
Inferred local ancestry is used for admixture mapping and population genetic analyses. We …
[HTML][HTML] RFMix: a discriminative modeling approach for rapid and robust local-ancestry inference
Local-ancestry inference is an important step in the genetic analysis of fully sequenced
human genomes. Current methods can only detect continental-level ancestry (ie, European …
human genomes. Current methods can only detect continental-level ancestry (ie, European …
[HTML][HTML] Enhanced methods for local ancestry assignment in sequenced admixed individuals
R Brown, B Pasaniuc - PLoS computational biology, 2014 - journals.plos.org
Inferring the ancestry at each locus in the genome of recently admixed individuals (eg,
Latino Americans) plays a major role in medical and population genetic inferences, ranging …
Latino Americans) plays a major role in medical and population genetic inferences, ranging …
[HTML][HTML] Comparing local ancestry inference models in populations of two-and three-way admixture
R Schubert, A Andaleon, HE Wheeler - PeerJ, 2020 - peerj.com
Local ancestry estimation infers the regional ancestral origin of chromosomal segments in
admixed populations using reference populations and a variety of statistical models …
admixed populations using reference populations and a variety of statistical models …
Fast and accurate inference of local ancestry in Latino populations
Y Baran, B Pasaniuc, S Sankararaman… - …, 2012 - academic.oup.com
Motivation: It is becoming increasingly evident that the analysis of genotype data from
recently admixed populations is providing important insights into medical genetics and …
recently admixed populations is providing important insights into medical genetics and …
[HTML][HTML] Estimating local ancestry in admixed populations
S Sankararaman, S Sridhar, G Kimmel… - The American Journal of …, 2008 - cell.com
Large-scale genotyping of SNPs has shown a great promise in identifying markers that
could be linked to diseases. One of the major obstacles involved in performing these studies …
could be linked to diseases. One of the major obstacles involved in performing these studies …
Loter: a software package to infer local ancestry for a wide range of species
Admixture between populations provides opportunity to study biological adaptation and
phenotypic variation. Admixture studies rely on local ancestry inference for admixed …
phenotypic variation. Admixture studies rely on local ancestry inference for admixed …
Fast model-based estimation of ancestry in unrelated individuals
Population stratification has long been recognized as a confounding factor in genetic
association studies. Estimated ancestries, derived from multi-locus genotype data, can be …
association studies. Estimated ancestries, derived from multi-locus genotype data, can be …
[HTML][HTML] Enhancements to the ADMIXTURE algorithm for individual ancestry estimation
DH Alexander, K Lange - BMC bioinformatics, 2011 - Springer
Background The estimation of individual ancestry from genetic data has become essential to
applied population genetics and genetic epidemiology. Software programs for calculating …
applied population genetics and genetic epidemiology. Software programs for calculating …
[HTML][HTML] Fast individual ancestry inference from DNA sequence data leveraging allele frequencies for multiple populations
V Bansal, O Libiger - BMC bioinformatics, 2015 - Springer
Background Estimation of individual ancestry from genetic data is useful for the analysis of
disease association studies, understanding human population history and interpreting …
disease association studies, understanding human population history and interpreting …