Pressure-driven spreadable deferoxamine-laden hydrogels for vascularized skin flaps

L Wu, S Gao, T Zhao, K Tian, T Zheng, X Zhang… - Biomaterials …, 2021 - pubs.rsc.org
The development of hydrogels that support vascularization to improve the survival of skin
flaps, yet establishing homogeneous angiogenic niches without compromising the ease of …

MSC‐Laden Composite Hydrogels for Inflammation and Angiogenic Regulation for Skin Flap Repair

L Wu, K Tian, Z Ding, T Zhao, X Zhang… - Advanced …, 2022 - Wiley Online Library
Abstract Pressure‐driven, spreadable, deferoxamine (DFO)‐laden hydrogels are developed
toward treatment for improved skin flap tissue repair. Further, mesenchymal stem cells …

Injectable silk nanofiber hydrogels for sustained release of small-molecule drugs and vascularization

Z Ding, M Zhou, Z Zhou, W Zhang, X Jiang… - ACS Biomaterials …, 2019 - ACS Publications
Strategies to control neovascularization in damaged tissues remain a key issue in
regenerative medicine. Unlike most reported desferrioxamine (DFO)-loaded systems where …

Silk Nanofiber Scaffolds with Multiple Angiogenic Cues to Accelerate Wound Regeneration

G Xu, L Xiao, P Guo, Y Wang, S Ke, G Lyu… - ACS Biomaterials …, 2023 - ACS Publications
Niches with multiple physical and chemical cues can influence the fate of cells and tissues in
vivo. Simulating the in vivo niche in the design of bioactive materials is a challenge …

Electrospun photocrosslinkable hydrogel fibrous scaffolds for rapid in vivo vascularized skin flap regeneration

X Sun, Q Lang, H Zhang, L Cheng… - Advanced Functional …, 2017 - Wiley Online Library
Distal necrosis of random skin flap is always clinical problematic in plastic surgery. The
development of 3D functional vascular networks is fundamental for the survival of a local …

Vascular induction and cell infiltration into peptide-modified bioactive silk fibroin hydrogels

Y Kambe, A Murakoshi, H Urakawa, Y Kimura… - Journal of Materials …, 2017 - pubs.rsc.org
In hydrogel-based soft tissue engineering, vascular induction into a hydrogel as well as long-
term volume retention is essential to maintain tissue shape and function without causing …

Injectable desferrioxamine-laden silk nanofiber hydrogels for accelerating diabetic wound healing

Z Ding, Y Zhang, P Guo, T Duan, W Cheng… - ACS Biomaterials …, 2021 - ACS Publications
Dysangiogenesis and chronic inflammation are two critical reasons for diabetic foot ulcers.
Desferrioxamine (DFO) was used clinically in the treatment of diabetic foot ulcers by …

Fibro‐gel: an all‐aqueous hydrogel consisting of microfibers with tunable release profile and its application in wound healing

Y Shen, Y Liu, JK Nunes, C Wang, M Xu… - Advanced …, 2023 - Wiley Online Library
Injectable hydrogels are valuable tools in tissue engineering and regenerative medicine due
to their unique advantages of injectability with minimal invasiveness and usability for …

Cell infiltrative hydrogel fibrous scaffolds for accelerated wound healing

X Zhao, X Sun, L Yildirimer, Q Lang, ZYW Lin, R Zheng… - Acta biomaterialia, 2017 - Elsevier
Abstract Development of natural protein-based fibrous scaffolds with tunable physical
properties and biocompatibility is highly desirable to construct three-dimensional (3D), fully …

[HTML][HTML] Human Keratinocytes and Fibroblasts Co-Cultured on Silk Fibroin Scaffolds Exosomally Overrelease Angiogenic and Growth Factors

P Hu, U Armato, G Freddi, A Chiarini, I Dal Prà - Cells, 2023 - mdpi.com
Objectives: The optimal healing of skin wounds, deep burns, and chronic ulcers is an
important clinical problem. Attempts to solve it have been driving the search for skin …