Genetic risk factors for endometriosis near estrogen receptor 1 and coexpression of genes in this region in endometrium
S Marla, S Mortlock, S Houshdaran… - Molecular human …, 2021 - academic.oup.com
The etiology and pathogenesis of endometriosis are complex with both genetic and
environmental factors contributing to disease risk. Genome-wide association studies …
environmental factors contributing to disease risk. Genome-wide association studies …
Association of an oestrogen receptor gene polymorphism in Chinese Han women with endometriosis and endometriosis-related infertility
W Wang, Y Li, M Maitituoheti, R Yang, Z Wu… - Reproductive …, 2013 - Elsevier
Endometriosis is a steroid-dependent complex disease. The oestrogen receptor plays an
important role by mediating oestrogen action and eutopic or ectopic endometrium …
important role by mediating oestrogen action and eutopic or ectopic endometrium …
Tissue specific regulation of transcription in endometrium and association with disease
STUDY QUESTION Are genetic effects on endometrial gene expression tissue specific
and/or associated with reproductive traits and diseases? SUMMARY ANSWER Analyses of …
and/or associated with reproductive traits and diseases? SUMMARY ANSWER Analyses of …
Identifying the biological basis of GWAS hits for endometriosis
JN Fung, PAW Rogers… - Biology of …, 2015 - academic.oup.com
Endometriosis is a common estrogen-dependent gynecological disease influenced by
multiple genetic and environmental factors. Genome-wide association studies (GWAS) have …
multiple genetic and environmental factors. Genome-wide association studies (GWAS) have …
The search for genes contributing to endometriosis risk
GW Montgomery, DR Nyholt, ZZ Zhao… - Human reproduction …, 2008 - academic.oup.com
BACKGROUND Genetic variation contributes to the risk of developing endometriosis. This
review summarizes gene mapping studies in endometriosis and the prospects of finding …
review summarizes gene mapping studies in endometriosis and the prospects of finding …
Genetics of endometriosis: State of the art on genetic risk factors for endometriosis
JN Fung, GW Montgomery - Best practice & research Clinical obstetrics & …, 2018 - Elsevier
Developments in high-throughput genotyping technology have driven discovery of genomic
regions associated with an increased risk of endometriosis. In all, 16 genomic regions have …
regions associated with an increased risk of endometriosis. In all, 16 genomic regions have …
Association between oestrogen receptor alpha (ESR1) gene polymorphisms and endometriosis: a meta-analysis of 24 case-control studies
L Zhao, C Gu, K Huang, W Fan, L Li, M Ye… - Reproductive …, 2016 - Elsevier
Abstract The PvuII (C> T), XbaI (A> G) and (TA) n polymorphisms of ESR1 gene are
potentially associated with susceptibility to endometriosis. A meta-analysis was conducted to …
potentially associated with susceptibility to endometriosis. A meta-analysis was conducted to …
[HTML][HTML] Insights from genomic studies on the role of sex steroids in the aetiology of endometriosis
PTK Saunders - Reproduction and Fertility, 2022 - raf.bioscientifica.com
Endometriosis is a chronic neuro-inflammatory disorder the defining feature of which is the
growth of tissue (lesions) that resembles the endometrium outside the uterus. Estimates of …
growth of tissue (lesions) that resembles the endometrium outside the uterus. Estimates of …
[HTML][HTML] Genetic regulation of transcription in the endometrium in health and disease
S Mortlock, B McKinnon… - Frontiers in Reproductive …, 2022 - frontiersin.org
The endometrium is a complex and dynamic tissue essential for fertility and implicated in
many reproductive disorders. The tissue consists of glandular epithelium and vascularised …
many reproductive disorders. The tissue consists of glandular epithelium and vascularised …
Ten estrogen-related polymorphisms and endometriosis: a study of multiple gene–gene interactions
A Huber, CC Keck, LA Hefler… - Obstetrics & …, 2005 - journals.lww.com
OBJECTIVE: Genetic as well as hormonal factors are known to influence the development
and clinical course of endometriosis. We aimed to investigate the association among 10 …
and clinical course of endometriosis. We aimed to investigate the association among 10 …
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