Comparative effects of different enzymatic hydrolysates of konjac glucomannan on gut flora and constipation in rats

X Chang, Y Liu, M Hu, Y Liu, C Jiang, Q Wang, Q Jin… - Food & Function, 2022 - pubs.rsc.org
This study aimed to compare the effects of different hydrolysates (named GKOS and MKOS)
on constipated rats, which were obtained by degradation from konjac glucomannan by β …

[HTML][HTML] Fecal fermentation behaviors of Konjac glucomannan and its impacts on human gut microbiota

X Tan, B Wang, X Zhou, C Liu, C Wang, J Bai - Food Chemistry: X, 2024 - Elsevier
Dietary fiber targets the regulation of the intestinal flora and thus affects host health,
however, the complex relationship between these factors lacks direct evidence. In this study …

Effect of konjac glucomannan on metabolites in the stomach, small intestine and large intestine of constipated mice and prediction of the KEGG pathway

Q Zhang, D Zhong, YY Ren, Z Meng, RB Pegg… - Food & Function, 2021 - pubs.rsc.org
The occurrence of constipation involves the whole gastrointestinal tract. Konjac
glucomannan (KGM) has been clinically proven to alleviate constipation, but its mechanism …

Konjac acts as a natural laxative by increasing stool bulk and improving colonic ecology in healthy adults

HL Chen, HC Cheng, YJ Liu, SY Liu, WT Wu - Nutrition, 2006 - Elsevier
OBJECTIVE: Konjac glucomannan (KGM) has been shown to relieve constipation, which
could be associated with increased stool bulk and improved colonic ecology. METHODS …

Amelioration of gut dysbiosis and gastrointestinal motility by konjac oligo-glucomannan on loperamide-induced constipation in mice

F Hayeeawaema, S Wichienchot, P Khuituan - Nutrition, 2020 - Elsevier
Objective Konjac oligo-glucomannan (KOG) is a non-digestible dietary fiber that is resistant
to digestion and absorption in gastrointestinal (GI) tract. Thus, it might be used as an …

Hypoglycemic effects of different molecular weight konjac glucomannans via intestinal microbiota and SCFAs mediated mechanism

J Deng, X Zou, Y Liang, J Zhong, K Zhou… - International Journal of …, 2023 - Elsevier
The hypoglycemic effects of konjac glucomannans (KGMs) are well recognized, and our
previous study showed KGMs with different molecular weight have different hypoglycemic …

Unhydrolyzed and hydrolyzed konjac glucomannans modulated cecal and fecal microflora in Balb/c mice

HL Chen, YH Fan, ME Chen, Y Chan - Nutrition, 2005 - Elsevier
OBJECTIVE: The prebiotic role of intact konjac glucomannan (KGM) is contradictory. Short-
chain glucomannan may cause a greater or faster effect on colonic microflora compared with …

Molecular properties and gut health benefits of enzyme-hydrolyzed konjac glucomannans

JY Yin, LY Ma, MY Xie, SP Nie, JY Wu - Carbohydrate polymers, 2020 - Elsevier
Konjac glucomannan (KGM) with a molecular weight (MW) of 823.4 kDa was partially
degraded by endo-1, 4-β-mannanase. Two hydrolyzed KGM fractions (KGM-M-1: 147.2 kDa …

Supplementation of konjac glucomannan into a low-fiber Chinese diet promoted bowel movement and improved colonic ecology in constipated adults: a placebo …

HL Chen, HC Cheng, WT Wu, YJ Liu… - Journal of the American …, 2008 - Taylor & Francis
Objectives: This diet-controlled study was designed to examine effects of konjac
glucomannan (KGM) supplement on the bowel habits and colonic ecology in 7 constipated …

Effects of konjac glucomannan hydrolysates on the gut microflora of mice

AA Elamir, RF Tester, FH Al‐Ghazzewi… - Nutrition & Food …, 2008 - emerald.com
Purpose–The aim of this study is to determine the effects of depolymerised mannans and
specifically konjac glucomannan hydrolysates (GMH) on the colonic microflora of mice …