Vascular calcification (VC) is characterized by calcium phosphate deposition in blood vessel
walls and is associated with many diseases, as well as increased cardiovascular morbidity …

Apoptosis of vascular smooth muscle cells plays an important role in vascular calcification
(VC). However, the potential mechanism remains poorly understood. Previous studies …

Objective: Vascular calcification is common among aging populations and mediated by
vascular smooth muscle cells (VSMCs). The endoplasmic reticulum (ER) is involved in …

Objectives—Aortic valve (AV) calcification occurs via a pathophysiological process that
includes lipoprotein deposition, inflammation, and osteoblastic differentiation of valvular …

Arterial calcification is highly prevalent, particularly in patients with end-stage renal disease
(ESRD). The osteogenic differentiation of vascular smooth muscle cells (VSMCs) is the …

Vascular calcification (VC) is highly correlated with cardiovascular disease morbidity and
mortality, but anti-VC treatment remains an area to be tackled due to the ill-defined …

Cardiovascular disease is the number one cause of death worldwide. A major underlying
cause of cardiovascular disease is atherosclerosis–a chronic inflammatory disease of the …

Background: Uremic vascular calcification (UVC) is reminiscent of osteogenesis and
apoptosis in vascular smooth muscle cell (VSMC). We aimed to identify how circulating …

Calcific aortic valve disease (CAVD), which is involved in osteogenic reprogramming of
valvular interstitial cells (VICs), is the most common form of valve disease. It still lacks …

We formerly proved that uremic vascular calcification (UVC) correlates tightly with oxidative
elastic lamina (EL) injury and two cell fates (apoptosis and osteocytic conversion) in smooth …