The adaptive immune system and associated inflammation are vital in surveillance and host
protection against internal and external threats, but can secondarily damage host tissues …

Regulatory T (Treg) cells are a special subpopulation of immunosuppressive T cells that are
essential for sustaining immune homeostasis. They maintain self‐tolerance, inhibit …

Glaucoma as the leading neurodegenerative disease leads to blindness in 3.6 million
people aged 50 years and older worldwide. For many decades, glaucoma therapy has …

A sustained neuroinflammatory response is the hallmark of many neurodegenerative
diseases, including Parkinson's disease, Alzheimer's disease, amyotrophic lateral sclerosis …

Neuroinflammation is involved in several neurodegenerative disorders and emerging
evidence indicates that it constitutes a critical process that is required for the progression of …

Emerging evidence demonstrates that adaptive immunity influences the pathobiology of
neurodegenerative disorders. Misfolded aggregated self-proteins can break immune …

Regulatory CD4+ CD25+ Foxp3+ T cells (Tregs) have been the focus of significant attention
for their role in controlling immune responses. Although knowledge of Treg biology has …

While inflammation may not be the cause of disease, it is well known that it contributes to
disease pathogenesis across a multitude of peripheral and central nervous system …

Regulatory T cells (Tregs) control inflammation and maintain immune homeostasis. The well-
characterised circulatory population of CD4+ Foxp3+ Tregs is effective at preventing …

Background Increasing evidence supports a key role for peripheral immune processes in the
pathophysiology of Alzheimer's disease (AD), highlighting an intricate interplay between …