Emerging functions within the enzyme families of plant alkaloid biosynthesis

F Muro-Villanueva, RS Nett - Phytochemistry Reviews, 2023 - Springer
The alkaloids are a major class of nitrogen-containing plant specialized metabolites that
function as both toxic defense compounds and useful pharmaceuticals. Understanding the …

Alkaloid biosynthesis: metabolism and trafficking

J Ziegler, PJ Facchini - Annu. Rev. Plant Biol., 2008 - annualreviews.org
Alkaloids represent a highly diverse group of compounds that are related only by the
occurrence of a nitrogen atom in a heterocyclic ring. Plants are estimated to produce …

The expanding universe of alkaloid biosynthesis

V De Luca, P Laflamme - Current Opinion in Plant Biology, 2001 - Elsevier
Characterization of many of the major gene families responsible for the generation of central
intermediates and for their decoration, together with the development of large genomics and …

Synthesis and trafficking of alkaloid biosynthetic enzymes

PJ Facchini, B St-Pierre - Current Opinion in Plant Biology, 2005 - Elsevier
The biosynthesis of plant natural products involves a large number of enzymes that create
and elaborate a bewildering array of chemical structures, which are generally involved in …

Integration of discovery and engineering in plant alkaloid research: Recent developments in elucidation, reconstruction, and repurposing biosynthetic pathways

VH Bui, CE Rodríguez-López, TTT Dang - Current opinion in plant biology, 2023 - Elsevier
Plants synthesize tens of thousands of bioactive nitrogen-containing compounds called
alkaloids, including some clinically important drugs in modern medicine. The discovery of …

Engineering plant alkaloid biosynthetic pathways: progress and prospects

TM Kutchan, S Frick, M Weid - … in Plant Biochemistry and Molecular Biology, 2008 - Elsevier
With the successful application of molecular genetic methods to the plant alkaloid field, we
now have sophisticated tools at our disposal to study regulation of enzymatic biosynthesis …

The cell and developmental biology of alkaloid biosynthesis

V De Luca, B St Pierre - Trends in plant science, 2000 - cell.com
Plants produce unique natural products as a result of gene mutation and subsequent
adaptation of metabolic pathways to create new secondary metabolites. However, their …

[HTML][HTML] Biocatalysts from alkaloid producing plants

H Kries, SE O'Connor - Current Opinion in Chemical Biology, 2016 - Elsevier
Highlights•Secondary metabolism of plants serves as a rich source for bioactive
molecules.•Alkaloid biosynthetic pathways are revealing remarkable new enzymatic …

[HTML][HTML] The scaffold-forming steps of plant alkaloid biosynthesis

BR Lichman - Natural Product Reports, 2021 - pubs.rsc.org
Alkaloids from plants are characterised by structural diversity and bioactivity, and maintain a
privileged position in both modern and traditional medicines. In recent years, there have …

[图书][B] New light on alkaloid biosynthesis and future prospects

N Giglioli-Guivarc'h - 2013 - books.google.com
Advances in Botanical Research publishes in-depth and up-to-date reviews on a wide range
of topics in plant sciences. Currently in its 68th volume, the series features varied reviews by …