Brown to white fat transition overlap with skeletal muscle during development of larger mammals: Is it a coincidence?

S Pani, S Dey, B Pati, U Senapati… - Journal of the Endocrine …, 2022 - academic.oup.com
In mammals, adipose tissues and skeletal muscles (SkMs) play a major role in the regulation
of energy homeostasis. Recent studies point to a possibility of dynamic interplay between …

[PDF][PDF] Brown adipose crosstalk in tissue plasticity and human metabolism

C Scheele, C Wolfrum - Endocrine reviews, 2020 - academic.oup.com
Infants rely on brown adipose tissue (BAT) as a primary source of thermogenesis. In some
adult humans, residuals of brown adipose tissue are adjacent to the central nervous system …

The ontogeny of brown adipose tissue

ME Symonds, M Pope, H Budge - Annual review of nutrition, 2015 - annualreviews.org
There are three different types of adipose tissue (AT)—brown, white, and beige—that differ
with stage of development, species, and anatomical location. Of these, brown AT (BAT) is …

Global gene expression profiling of brown to white adipose tissue transformation in sheep reveals novel transcriptional components linked to adipose remodeling

AL Basse, K Dixen, R Yadav, MP Tygesen, K Qvortrup… - BMC genomics, 2015 - Springer
Background Large mammals are capable of thermoregulation shortly after birth due to the
presence of brown adipose tissue (BAT). The majority of BAT disappears after birth and is …

Adipose tissue development during early life: novel insights into energy balance from small and large mammals

ME Symonds, M Pope, H Budge - Proceedings of the Nutrition …, 2012 - cambridge.org
Since the rediscovery of brown adipose tissue (BAT) in adult human subjects in 2007, there
has been a dramatic resurgence in research interest in its role in heat production and …

Double Myod and Igf2 inactivation promotes brown adipose tissue development by increasing Prdm16 expression

M Borensztein, S Viengchareun, D Montarras… - Faseb …, 2012 - hal.umontpellier.fr
Brown fat or brown adipose tissue (BAT), found in newborn mammals as small depots
localized in the interscapular region, plays a prominent role in regulating thermogenesis …

Browning attenuates murine white adipose tissue expansion during postnatal development

D Lasar, A Julius, T Fromme, M Klingenspor - Biochimica et Biophysica …, 2013 - Elsevier
During postnatal development of mice distinct white adipose tissue depots display a
transient appearance of brown-like adipocytes. These brite (brown in white) adipocytes …

Adipose organ development and remodeling

S Cinti - Comprehensive Physiology, 2018 - iris.univpm.it
During the last decades, research on adipose tissues has spread in parallel with the
extension of obesity. Several observations converged on the idea that adipose tissues are …

Brown fat and obesity: the next big thing?

M Stephens, M Ludgate, DA Rees - Clinical endocrinology, 2011 - Wiley Online Library
Brown adipose tissue (BAT) is well recognised to have an important role in the maintenance
of body temperature in animals and human neonates, its thermogenic action affected by a …

[HTML][HTML] Adipogenesis: new insights into brown adipose tissue differentiation

S Carobbio, B Rosen… - Journal of molecular …, 2013 - jme.bioscientifica.com
Confirmation of the presence of functional brown adipose tissue (BAT) in humans has
renewed interest in investigating the potential therapeutic use of this tissue. The finding that …