MDR1 C3435T polymorphism and cancer risk: a meta-analysis based on 39 case–control studies
X Sheng, L Zhang, N Tong, D Luo, M Wang, M Xu… - Molecular biology …, 2012 - Springer
Abstract Multidrug resistance 1 (MDR1) gene encodes the ATP-dependent cellular efflux
pump P-glycoprotein (P-gp) which efflux of a variety of substances across the membrane. P …
pump P-glycoprotein (P-gp) which efflux of a variety of substances across the membrane. P …
MDR1 gene C3435T polymorphism and cancer risk: a meta-analysis of 34 case–control studies
J Wang, B Wang, J Bi, K Li, J Di - Journal of cancer research and clinical …, 2012 - Springer
Background P-glycoprotein, the product of the MDR1 gene, is a transmembrane active efflux
pump for a variety of environmental toxins and xenobiotics. Epidemiological studies have …
pump for a variety of environmental toxins and xenobiotics. Epidemiological studies have …
The association between polymorphisms in the MDR1 gene and risk of cancer: a systematic review and pooled analysis of 52 case–control studies
LH Wang, YB Song, WL Zheng, L Jiang, WL Ma - Cancer cell international, 2013 - Springer
Background The multidrug resistance (MDR) 1 gene encodes a 170-kDa membrane
transporter called P-glycoprotein, which plays an important role in protecting cells against …
transporter called P-glycoprotein, which plays an important role in protecting cells against …
Association of C3435T Single-Nucleotide Polymorphism of MDR1 Gene with Breast Cancer in an Iranian Population
The human multidrug resistance gene 1 (MDR1) encodes a plasma membrane, P-
glycoprotein (Pgp), which functions as the transmembrane efflux pump for various …
glycoprotein (Pgp), which functions as the transmembrane efflux pump for various …
A polymorphism C3435T of the MDR-1 gene associated with smoking or high body mass index increases the risk of sporadic breast cancer in women
P Zubor, Z Lasabova, J Hatok… - Oncology …, 2007 - spandidos-publications.com
The human multidrug resistance gene 1 (MDR-1) encodes a plasma membrane P-
glycoprotein (P-gp) that functions as the transmembrane efflux pump for various structurally …
glycoprotein (P-gp) that functions as the transmembrane efflux pump for various structurally …
Variant genotypes of MDR1 C3435T increase the risk of leukemia: evidence from 10 case–control studies
X Qian, S Cao, G Yang, J Dong, G Jin… - Leukemia & …, 2012 - Taylor & Francis
Abstract The C3435T (Ile1142Ile) polymorphism of the multidrug resistance gene (MDR1)
has been implicated in leukemia risk, but the reported results are inconsistent. Here we …
has been implicated in leukemia risk, but the reported results are inconsistent. Here we …
Association between the MDR1 gene variant C3435T and risk of leukaemia: a meta‐analysis
BB Zhang, C Xuan, KF Deng, N Wu… - European Journal of …, 2013 - Wiley Online Library
Although a number of genetic studies have attempted to link the multidrug resistance
(MDR1) C 3435 T polymorphism to risk of leukaemia, the results were often inconsistent …
(MDR1) C 3435 T polymorphism to risk of leukaemia, the results were often inconsistent …
Association between MDR1 C3435T polymorphism and colorectal cancer risk: A meta-analysis
SS Jin, WJ Song - Medicine, 2017 - journals.lww.com
Background: The multidrug resistance gene 1 (MDR1) C3435T polymorphism has been
reported to be associated with colorectal cancer (CRC) risk in Asians, however the results …
reported to be associated with colorectal cancer (CRC) risk in Asians, however the results …
MDR1 (C3435T) polymorphism: relation to the risk of breast cancer and therapeutic outcome
M Cizmarikova, M Wagnerova, L Schonova… - The …, 2010 - nature.com
Abstract P-glycoprotein (PGP), the product of the MDR1 gene, is a transmembrane active
efflux pump for a variety of carcinogens and cytostatics. It has been suggested that MDR1 …
efflux pump for a variety of carcinogens and cytostatics. It has been suggested that MDR1 …
Association between MDR1 C3435T polymorphism and risk of breast cancer
Z Wang, T Wang, J Bian - Gene, 2013 - Elsevier
Abstract The C3435T (rs1045642) polymorphism, located in multi-drug resistance gene 1
(MDR1), has demonstrated its role in decreasing the P-gp activity level which is related to …
(MDR1), has demonstrated its role in decreasing the P-gp activity level which is related to …