Is depression the missing link between inflammatory mediators and cancer?

B Polityńska, O Pokorska, AM Wojtukiewicz… - Pharmacology & …, 2022 - Elsevier
Patients with cancer are at greater risk of developing depression in comparison to the
general population and this is associated with serious adverse effects, such as poorer …

Biological mechanisms of cancer-induced depression

K Young, G Singh - Frontiers in psychiatry, 2018 - frontiersin.org
Patients with cancer are more likely to develop depression than the general population,
which negatively impacts their quality of life and prognosis. In order to identify effective …

The biology of depression in cancer and the relationship between depression and cancer progression

JL Sotelo, D Musselman, C Nemeroff - International Review of …, 2014 - Taylor & Francis
The prevalence of depressive symptoms in patients with cancer exceeds that observed in
the general population and depression is associated with a poorer prognosis in cancer …

Depression as a risk factor for cancer: from pathophysiological advances to treatment implications

MB Currier, CB Nemeroff - Annual review of medicine, 2014 - annualreviews.org
Innate immune activation and inflammation have been posited to play a role in the
pathophysiology of both depression and neoplastic growth. Cancer patients experience a …

[PDF][PDF] The role of depression and neuroimmune axis in the prognosis of cancer patients

M Aldea, L Craciun, C Tomuleasa, C Crivii - J BUON, 2014 - researchgate.net
New exciting research in psycho-oncology has shed light on the mechanisms by which
biobehavioral signaling in cancer interplays with the neuroimmune axis, as well as on the …

Depression in cancer: the many biobehavioral pathways driving tumor progression

B Bortolato, TN Hyphantis, S Valpione, G Perini… - Cancer treatment …, 2017 - Elsevier
Abstract Major Depressive Disorder (MDD) is common among cancer patients, with
prevalence rates up to four-times higher than the general population. Depression confers …

Depression in cancer patients: Pathogenesis, implications and treatment

HR Smith - Oncology letters, 2015 - spandidos-publications.com
Depression is a common comorbidity in cancer cases, affecting> 10% of patients. A cancer
diagnosis is life‑changing, and is a source of considerable psychological and emotional …

Depression and cancer: mechanisms and disease progression

D Spiegel, J Giese-Davis - Biological psychiatry, 2003 - Elsevier
Depression and cancer commonly co-occur. The prevalence of depression among cancer
patients increases with disease severity and symptoms such as pain and fatigue. The …

Depression in cancer: new developments regarding diagnosis and treatment

CL Raison, AH Miller - Biological psychiatry, 2003 - Elsevier
Considerable data demonstrate the high prevalence of symptoms of depression in patients
with a wide variety of neoplastic disorders. Moreover, the dire consequences of these …

Biomarker opportunities in the treatment of cancer-related depression

AA Panjwani, S Aguiar, B Gascon, DG Brooks… - Trends in Molecular …, 2022 - cell.com
Depression comorbid with cancer is common and associated with a host of negative health
outcomes. The inflammatory basis of depression is a growing area of research in cancer …