Microfluidic Label‐Free Hydrodynamic Separation of Blood Cells: Recent Developments and Future Perspectives

S Lee, H Kim, S Yang - Advanced Materials Technologies, 2023 - Wiley Online Library
The biophysical characteristics and counts of blood cells provide useful information
regarding pathological conditions. Therefore, the separation of blood components is a …

Hydrodynamic mechanisms of cell and particle trapping in microfluidics

A Karimi, S Yazdi, AM Ardekani - Biomicrofluidics, 2013 - pubs.aip.org
Focusing and sorting cells and particles utilizing microfluidic phenomena have been
flourishing areas of development in recent years. These processes are largely beneficial in …

Microfluidic hydrodynamic cell separation: a review

Z Wu, K Hjort - Micro and Nanosystems, 2009 - ingentaconnect.com
Microfluidic continuous cell separation based on hydrodynamic interaction in a microfluidic
channel has attracted attention because of its robustness, high throughput and cell viability …

Passive microfluidic devices for cell separation

T Zhang, D Di Carlo, CT Lim, T Zhou, G Tian… - Biotechnology …, 2024 - Elsevier
The separation of specific cell populations is instrumental in gaining insights into cellular
processes, elucidating disease mechanisms, and advancing applications in tissue …

Microfluidic blood cell sorting: now and beyond

ZTF Yu, KM Aw Yong, J Fu - Small, 2014 - Wiley Online Library
Blood plays an important role in homeostatic regulation with each of its cellular components
having important therapeutic and diagnostic uses. Therefore, separation and sorting of …

Continuous separation of cells and particles in microfluidic systems

A Lenshof, T Laurell - Chemical Society Reviews, 2010 - pubs.rsc.org
The progress in microfabrication and lab-on-a-chip technologies has been a major area of
development for new approaches to bioanalytics and integrated concepts for cell biology …

Microfluidic‐based approaches in targeted cell/particle separation based on physical properties: fundamentals and applications

R Nasiri, A Shamloo, S Ahadian, L Amirifar, J Akbari… - Small, 2020 - Wiley Online Library
Cell separation is a key step in many biomedical research areas including biotechnology,
cancer research, regenerative medicine, and drug discovery. While conventional cell sorting …

[HTML][HTML] Label-free microfluidic sorting of microparticles

J Zhou, P Mukherjee, H Gao, Q Luan… - APL bioengineering, 2019 - pubs.aip.org
Massive growth of the microfluidics field has triggered numerous advances in focusing,
separating, ordering, concentrating, and mixing of microparticles. Microfluidic systems …

Microfluidic sorting of microtissues

DG Buschke, P Resto, N Schumacher, B Cox… - …, 2012 - pubs.aip.org
Increasingly, invitro culture of adherent cell types utilizes three-dimensional (3D) scaffolds or
aggregate culture strategies to mimic tissue-like, microenvironmental conditions. In parallel …

Microfluidic channel optimization to improve hydrodynamic dissociation of cell aggregates and tissue

X Qiu, JH Huang, TM Westerhof, JA Lombardo… - Scientific reports, 2018 - nature.com
Maximizing the speed and efficiency at which single cells can be liberated from tissues
would dramatically advance cell-based diagnostics and therapies. Conventional methods …