Drug excretion into breast milk—overview

S Ito, A Lee - Advanced drug delivery reviews, 2003 - Elsevier
Breastfeeding is the optimal form of infant feeding for the first months of an infant's life, and
the majority of healthy women initiate breastfeeding after the birth of their infant. However …

Modeling drug passage into human milk

PO Anderson, JB Sauberan - Clinical Pharmacology & …, 2016 - Wiley Online Library
Breastfeeding has positive health consequences for both the breastfed infant and the
nursing mother. 1, 2 Although information on drug use during lactation is available through …

Studying drugs in human milk: time to unify the approach

EJ Begg, SB Duffull, LP Hackett… - Journal of Human …, 2002 - journals.sagepub.com
The trend globally for mothers to breastfeed has highlighted the need for information on drug
transfer into breast milk and the extent to which the suckling neonate may be exposed and …

The transfer of drugs and therapeutics into human breast milk: an update on selected topics

HC Sachs, Committee on Drugs, DAC Frattarelli… - …, 2013 - publications.aap.org
Many mothers are inappropriately advised to discontinue breastfeeding or avoid taking
essential medications because of fears of adverse effects on their infants. This cautious …

Using pharmacokinetics to predict the effects of pregnancy and maternal–infant transfer of drugs during lactation

GD Anderson - Expert opinion on drug metabolism & toxicology, 2006 - Taylor & Francis
Knowledge of pharmacokinetics and the use of a mechanistic-based approach can improve
our ability to predict the effects of pregnancy for medications when data are limited. Despite …

A comprehensive review of assay methods to determine drugs in breast milk and the safety of breastfeeding when taking drugs

B Fríguls, X Joya, O García-Algar, CR Pallás… - Analytical and …, 2010 - Springer
Most of the licit and illicit drugs consumed by the breastfeeding woman pass into the milk
and can modify the production, volume and composition of the milk, as well as hypothetically …

Infant drug exposure via breast milk

RHJ Verstegen, PO Anderson… - British Journal of Clinical …, 2022 - Wiley Online Library
More than half of women take medications during breastfeeding, predisposing their infants
to medication exposure via breast milk. As a result, adverse drug reactions may emerge in …

Neonatal exposure to drugs in breast milk

PJ McNamara, M Abbassi - Pharmaceutical research, 2004 - Springer
There are many benefits of breast-feeding both for the infant and for the mother. Nursing
mothers who are also taking medications or exposed to environmental hazards may be …

Drugs in lactation

RHJ Verstegen, S Ito - Journal of Obstetrics and Gynaecology …, 2019 - Wiley Online Library
Although most medications can be taken safely during breastfeeding, potential risks of infant
toxicity do exist because all medications will be excreted into the breast milk to some extent …

Excretion of psychotropic drugs into breast milk: pharmacokinetic overview and therapeutic implications

O Spigset, S Hägg - CNS drugs, 1998 - Springer
The prescription of psychotropic drugs during lactation is a clinically important but complex
issue. Most of the information available on the excretion of these drugs into breast milk and …