[HTML][HTML] Chemical and mechanical activation of resident cardiac macrophages in the living myocardial slice ex vivo model
FJG Waleczek, M Sansonetti, K Xiao, M Jung… - Basic Research in …, 2022 - Springer
Resident cardiac macrophages (rcMACs) are among the most abundant immune cells in the
heart. Plasticity and activation are hallmarks of rcMACs in response to changes in the …
heart. Plasticity and activation are hallmarks of rcMACs in response to changes in the …
[HTML][HTML] Resident cardiac macrophages mediate adaptive myocardial remodeling
NR Wong, J Mohan, BJ Kopecky, S Guo, L Du, J Leid… - Immunity, 2021 - cell.com
Cardiac macrophages represent a heterogeneous cell population with distinct origins,
dynamics, and functions. Recent studies have revealed that CC Chemokine Receptor 2 …
dynamics, and functions. Recent studies have revealed that CC Chemokine Receptor 2 …
Crosstalk Between Cardiac Cells and Macrophages Postmyocardial Infarction: Insights from In Vitro Studies
P Hitscherich, EJ Lee - Tissue Engineering Part B: Reviews, 2021 - liebertpub.com
Cardiovascular disease, including myocardial infarction (MI), is the leading cause of death in
the western world. Following MI, a large number of cardiomyocytes are lost and …
the western world. Following MI, a large number of cardiomyocytes are lost and …
Proliferation and recruitment contribute to myocardial macrophage expansion in chronic heart failure
Rationale: Macrophages reside in the healthy myocardium, participate in ischemic heart
disease, and modulate myocardial infarction (MI) healing. Their origin and roles in post-MI …
disease, and modulate myocardial infarction (MI) healing. Their origin and roles in post-MI …
[HTML][HTML] Isolation of macrophage subsets and stromal cells from human and mouse myocardial specimens
Macrophages represent the most heterogeneous and abundant immune cell populations in
the heart and are central in driving inflammation and reparative responses after cardiac …
the heart and are central in driving inflammation and reparative responses after cardiac …
[HTML][HTML] Resident cardiac macrophages: crucial modulators of cardiac (patho) physiology
M Sansonetti, FJG Waleczek, M Jung, T Thum… - Basic Research in …, 2020 - Springer
Resident cardiac macrophages (rcMacs) are integral components of the myocardium where
they have key roles for tissue homeostasis and in response to inflammation, tissue injury …
they have key roles for tissue homeostasis and in response to inflammation, tissue injury …
Resident macrophages and their potential in cardiac tissue engineering
M Suku, L Forrester, M Biggs… - Tissue Engineering Part …, 2022 - liebertpub.com
Many facets of tissue engineered models aim at understanding cellular mechanisms to
recapitulate in vivo behavior, to study and mimic diseases for drug interventions, and to …
recapitulate in vivo behavior, to study and mimic diseases for drug interventions, and to …
Cardiac resident macrophages prevent fibrosis and stimulate angiogenesis
Rationale: The initial hypertrophy response to cardiac pressure overload is considered
compensatory, but with sustained stress, it eventually leads to heart failure. Recently, a role …
compensatory, but with sustained stress, it eventually leads to heart failure. Recently, a role …
[HTML][HTML] Macrophage-driven cardiac inflammation and healing: insights from homeostasis and myocardial infarction
W Zuo, R Sun, Z Ji, G Ma - Cellular & Molecular Biology Letters, 2023 - Springer
Early and prompt reperfusion therapy has markedly improved the survival rates among
patients enduring myocardial infarction (MI). Nonetheless, the resulting adverse remodeling …
patients enduring myocardial infarction (MI). Nonetheless, the resulting adverse remodeling …
Activated macrophages decrease rat cardiac myocyte contractility: importance of ICAM-1-dependent adhesion
MG Simms, KR Walley - American Journal of Physiology …, 1999 - journals.physiology.org
Macrophages are found in the heart as part of the inflammatory response. To determine
whether macrophages could contribute to myocardial dysfunction, rat ventricular myocytes …
whether macrophages could contribute to myocardial dysfunction, rat ventricular myocytes …