The number of applications of dextran fractions and derivatives in medicine and medical
research has grown considerably over the years. Most of the physical properties of dextran …

SOLUTIONS of degraded dextran have been shown to be a promising plasma substitute in a
number of clinical trials. The practical problem in designing this substitute is to select dextran …

558 Proceedlings of the Royal Society of Medicine 8 interpretation somewhat difficult. We
are left guessing as to whether the elongated molecule is likely to penetrate a membrane" …

Acid-hydrolyzed dextran has proved an acceptable blood volume expander when
fractionated to the proper molecular size. Because it is used intravenously, care-ful attention …

Partially hydrolyzed preparations of the bacterial polysaccharide, dextran, have been shown
to be useful as non-toxic, osmotically active agents for expanding plasma volume in animals …

Large infusions of a 10% solution of dextran of molecular weight 40,000 were given to dogs
during 3 min using a specially designed apparatus. The initial expansion of plasma volume …

Dextran metabolism was evaluated in euvolemic and hemorrhaged rabbits following
administration of a 7.5% NaCl/6% Dextran‐70 (HSD) solution. Control rabbits and those …

This review deals with the pharmacokinetics of dextrans and hydroxyethylstarch, the most
commonly used plasma expanders. The complex composition of these colloidal agents …

Dextran was introduced in 1945 as a colloidal infusion solution to be used as a plasma
volume expander [GRNWALL and INGELMAN, 1945]. It is a polymer of glucose and it is …

Dextran is a polysaccharide formed by the action of an enzyme on sucrose. It consists of
glucose units linked together by alpha 1-6 bonds. At intervals of about 20 glucose units …