Biologic therapy for inflammatory bowel disease

S Ardizzone, GB Porro - Drugs, 2005 - Springer
Despite all of the advances in our understanding of the pathophysiology of inflammatory
bowel disease (IBD), we still do not know its cause. Some of the most recently available data …

[HTML][HTML] Current view of the immunopathogenesis in inflammatory bowel disease and its implications for therapy

MI Torres, A Rios - World journal of gastroenterology: WJG, 2008 - ncbi.nlm.nih.gov
Although the aetiology of inflammatory bowel disease (IBD) remains unknown, the
pathogenesis is gradually being unravelled, seeming to be the result of a combination of …

Management of inflammatory bowel disease with infliximab and other anti-tumor necrosis factor alpha therapies

F Magro, F Portela - BioDrugs, 2010 - Springer
Inflammatory bowel disease (IBD), most commonly referring to Crohn's disease and
ulcerative colitis, is a chronic and disabling condition with an increasing incidence in …

Inflammatory bowel disease: epidemiology, pathogenesis, and therapeutic opportunities

SB Hanauer - Inflammatory bowel diseases, 2006 - academic.oup.com
Ulcerative colitis (UC) and Crohn's disease (CD), the primary constituents of inflammatory
bowel disease (IBD), are precipitated by a complex interaction of environmental, genetic …

A State-of-the-Art Review of New and Emerging Therapies for the Treatment of IBD

KO Chudy-Onwugaje, KE Christian… - Inflammatory bowel …, 2019 - academic.oup.com
Over the last 2 decades, novel therapies targeting several immune pathways have been
developed for the treatment of patients with inflammatory bowel disease (IBD). Although anti …

Biologic therapies in inflammatory bowel disease

LB Cohen, RM Nanau, F Delzor, MG Neuman - Translational Research, 2014 - Elsevier
Inflammatory bowel disease, including its 2 entities ulcerative colitis and Crohn's disease, is
a chronic medical condition characterized by the destructive inflammation of the intestinal …

Inflammation in the intestinal tract: pathogenesis and treatment

RS Blumberg - Digestive diseases, 2009 - karger.com
Over the past decade a major hypothesis has emerged for the etiopathogenesis of
inflammatory bowel disease (IBD). This hypothesis proposes that IBD represents a …

Immunopathogenesis of inflammatory bowel disease and mechanisms of biological therapies

B Ahluwalia, L Moraes, MK Magnusson… - Scandinavian journal of …, 2018 - Taylor & Francis
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal
tract with a multifactorial pathophysiology. Full comprehension of IBD pathology is still out of …

Biologic targeting in the treatment of inflammatory bowel diseases

M Bosani, S Ardizzone, GB Porro - Biologics: Targets and Therapy, 2009 - Taylor & Francis
The etiology of inflammatory bowel disease (IBD) has not yet been clarified and
immunosuppressive agents which nonspecifically reduce inflammation and immunity have …

The immune response in inflammatory bowel disease

SJ Brown, L Mayer - Official journal of the American College of …, 2007 - journals.lww.com
Ulcerative colitis (UC) and Crohn's disease (CD), collectively referred to as inflammatory
bowel disease (IBD), present with differing histologic and cytokine profiles. While the precise …