[HTML][HTML] Molecular mechanisms of inflammation in sarcopenia: diagnosis and therapeutic update

GE Jimenez-Gutierrez, LE Martínez-Gómez… - Cells, 2022 - mdpi.com
Sarcopenia is generally an age-related condition that directly impacts the quality of life. It is
also related to chronic diseases such as metabolic dysfunction associated with diabetes and …

[HTML][HTML] Experimental models of sarcopenia: bridging molecular mechanism and therapeutic strategy

S Mankhong, S Kim, S Moon, HB Kwak, DH Park… - Cells, 2020 - mdpi.com
Sarcopenia has been defined as a progressive decline of skeletal muscle mass, strength,
and functions in elderly people. It is accompanied by physical frailty, functional disability …

[HTML][HTML] Sarcopenia: Current treatments and new regenerative therapeutic approaches

JH Lo, T Yiu, MT Ong, WY Lee - Journal of orthopaedic translation, 2020 - Elsevier
Sarcopenia is characterized by loss of muscle and reduction in muscle strength that
contributes to higher mortality rate and increased incidence of fall and hospitalization in the …

Multi-omics research in sarcopenia: Current progress and future prospects

JC Liu, SS Dong, H Shen, DY Yang, BB Chen… - Ageing Research …, 2022 - Elsevier
Sarcopenia is a systemic disease with progressive and generalized skeletal muscle
dysfunction defined by age-related low muscle mass, high content of muscle slow fibers, and …

Understanding of sarcopenia: from definition to therapeutic strategies

JW Kim, R Kim, H Choi, SJ Lee, GU Bae - Archives of pharmacal research, 2021 - Springer
Sarcopenia refers to the gradual loss of skeletal muscle mass and function along with aging
and is a social burden due to growing healthcare cost associated with a super-aging society …

[HTML][HTML] Cellular senescence in sarcopenia: possible mechanisms and therapeutic potential

Y He, W Xie, H Li, H Jin, Y Zhang, Y Li - Frontiers in Cell and …, 2022 - frontiersin.org
Aging promotes most degenerative pathologies in mammals, which are characterized by
progressive decline of function at molecular, cellular, tissue, and organismal levels and …

[HTML][HTML] Sarcopenia and muscle aging: a brief overview

T Dao, AE Green, YA Kim, SJ Bae, KT Ha… - Endocrinology and …, 2020 - ncbi.nlm.nih.gov
The world is facing the new challenges of an aging population, and understanding the
process of aging has therefore become one of the most important global concerns …

Advances in research on pharmacotherapy of sarcopenia

Y Feike, L Zhijie, C Wei - Aging Medicine, 2021 - Wiley Online Library
Sarcopenia is a comprehensive degenerative disease with the progressive loss of skeletal
muscle mass with age, accompanied by the loss of muscle strength and muscle dysfunction …

[HTML][HTML] Sarcopenia: molecular pathways and potential targets for intervention

J Pascual-Fernández, A Fernández-Montero… - International Journal of …, 2020 - mdpi.com
Aging is associated with sarcopenia. The loss of strength results in decreased muscle mass
and motor function. This process accelerates the progressive muscle deterioration observed …

[HTML][HTML] Inflammaging: implications in sarcopenia

E Antuña, C Cachán-Vega, JC Bermejo-Millo… - International Journal of …, 2022 - mdpi.com
In a world in which life expectancy is increasing, understanding and promoting healthy
aging becomes a contemporary demand. In the elderly, a sterile, chronic and low-grade …