[HTML][HTML] Galleria mellonella as a Suitable Model of Bacterial Infection: Past, Present and Future

G Ménard, A Rouillon, V Cattoir… - Frontiers in cellular and …, 2021 - frontiersin.org
The increasing interest for Galleria mellonella larvae as an infection model is evidenced by
the number of papers reporting its use, which increases exponentially since the early 2010s …

Galleria mellonella as an infection model: an in-depth look at why it works and practical considerations for successful application

MF Pereira, CC Rossi, GC da Silva… - Pathogens and …, 2020 - academic.oup.com
The larva of the greater wax moth Galleria mellonella is an increasingly popular model for
assessing the virulence of bacterial pathogens and the effectiveness of antimicrobial agents …

The insect Galleria mellonella as a powerful infection model to investigate bacterial pathogenesis

N Ramarao, C Nielsen-Leroux, D Lereclus - JoVE (Journal of Visualized …, 2012 - jove.com
The study of bacterial virulence often requires a suitable animal model. Mammalian models
of infection are costly and may raise ethical issues. The use of insects as infection models …

Galleria mellonella–intracellular bacteria pathogen infection models: the ins and outs

M Asai, Y Li, SM Newton, BD Robertson… - FEMS Microbiology …, 2023 - academic.oup.com
Galleria mellonella (greater wax moth) larvae are used widely as surrogate infectious
disease models, due to ease of use and the presence of an innate immune system …

[HTML][HTML] Galleria mellonella: The Versatile Host for Drug Discovery, In Vivo Toxicity Testing and Characterising Host-Pathogen Interactions

M Piatek, G Sheehan, K Kavanagh - Antibiotics, 2021 - mdpi.com
Larvae of the greater wax moth, Galleria mellonella, are a convenient in vivo model for
assessing the activity and toxicity of antimicrobial agents and for studying the immune …

From moths to caterpillars: Ideal conditions for Galleria mellonella rearing for in vivo microbiological studies

AL Jorjão, LD Oliveira, L Scorzoni… - Virulence, 2018 - Taylor & Francis
Galleria mellonella is a well-accepted insect model for the study of pathogen-host
interactions and antimicrobial compounds. The main advantages of this model include the …

Galleria mellonella as a model host for microbiological and toxin research

OL Champion, S Wagley, RW Titball - Virulence, 2016 - Taylor & Francis
Mammals are widely used by microbiologists as a model host species to study infectious
diseases of humans and domesticated livestock. These studies have been pivotal for our …

Galleria mellonella as a model host for human pathogens: Recent studies and new perspectives

JC Junqueira - Virulence, 2012 - Taylor & Francis
The number of studies using G. mellonella as a model host for human pathogens has
increased significantly in the last few years. Important studies were published from different …

Galleria mellonella infection models for the study of bacterial diseases and for antimicrobial drug testing

CJY Tsai, JMS Loh, T Proft - Virulence, 2016 - Taylor & Francis
abstract Galleria mellonella (greater wax moth or honeycomb moth) has been introduced as
an alternative model to study microbial infections. G. mellonella larvae can be easily and …

A powerful in vivo alternative model in scientific research: Galleria mellonella

P Singkum, S Suwanmanee, P Pumeesat… - Acta Microbiologica et …, 2019 - akjournals.com
Murine models are suggested as the gold standard for scientific research, but they have
many limitations of ethical and logistical concern. Then, the alternative host models have …