Passage of aerosol around or through a facemask can result in deposition on the face and in
the eyes. The present study quantified facial and eye deposition in a model simulating drug …

Nebulizers are often interfaced to patients using facemasks, especially when the patient is
sick and uncooperative. Tight-fitting masks are thought to improve drug delivery, but recent …

It has been shown in vitro that even a small air leak in the facemask can drastically reduce
the efficiency of drug delivery. In addition, it has been shown that drug deposition on the face …

Background In vivo case reports and in vitro studies have indicated that aerosol therapy
using face masks can result in drug deposition on the face and in the eyes, and that face …

Background: Aerosol masks were originally developed for adults and downsized for
children. Overall fit to minimize dead space and a tight seal are problematic, because …

We have quantified in vitro the influence of the facemask on the amount of drug delivered
(eg, inhaled mass) by jet nebulizer and pressurized metered dose inhaler (pMDI) valved …

The currently available facemask interface for the Nebuchamber (N) valved‐holding
chamber (VHC) provides a very poor seal to the face, which, on average, decreases the …

Background: Aerosol drug delivery to infants is a strong function of their behavior. Infants
can be active during medication administration, changing head position or breathing mode …

BACKGROUND: Aerosol face mask design and the distance at which the face mask is held
from the face affect the delivery of nebulized medication to pediatric patients. OBJECTIVE …

The laboratory evaluation of inhalers with facemasks for patient interface is so complex that
testing without a facemask is generally undertaken, a practice that has been advocated in …