Coevolution of morphology and virulence in Candida species

DS Thompson, PL Carlisle, D Kadosh - Eukaryotic cell, 2011 - Am Soc Microbiol
Many of the major human fungal pathogens are known to undergo morphological changes,
which in certain cases are associated with virulence. Although there has been an intense …

Candida morphogenesis and host–pathogen interactions

M Whiteway, U Oberholzer - Current opinion in microbiology, 2004 - Elsevier
The human fungal pathogen Candida albicans has many morphological forms. Recent
advances in genomics and cell biology are providing an improved understanding of the …

Linking Cellular Morphogenesis with Antifungal Treatment and Susceptibility in Candida Pathogens

J Sharma, S Rosiana, I Razzaq, RS Shapiro - Journal of Fungi, 2019 - mdpi.com
Fungal infections are a growing public health concern, and an increasingly important cause
of human mortality, with Candida species being amongst the most frequently encountered of …

[HTML][HTML] Recent advances in understanding Candida albicans hyphal growth

RA Arkowitz, M Bassilana - F1000Research, 2019 - ncbi.nlm.nih.gov
Morphological changes are critical for the virulence of a range of plant and human fungal
pathogens. Candida albicans is a major human fungal pathogen whose ability to switch …

Virulence in Candida species

K Haynes - Trends in microbiology, 2001 - cell.com
Candida species other than Candida albicans now account for up to 50% of deep
candidiasis cases, yet little attention has been paid to the virulence attributes of these fungi …

The Missing Link between Candida albicans Hyphal Morphogenesis and Host Cell Damage

D Wilson, JR Naglik, B Hube - PLoS pathogens, 2016 - journals.plos.org
Fungal pathogens are more commonly associated with morbidity and mortality than
generally appreciated. In fact, a significant portion of the world population is infected by …

Regulatory mechanisms controlling morphology and pathogenesis in Candida albicans

D Kadosh - Current opinion in microbiology, 2019 - Elsevier
Highlights•There is a strong association between C. albicans morphology and virulence.•C.
albicans morphology control mechanisms may serve as important antifungal …

Adaptation of Candida albicans to the host environment: the role of morphogenesis in virulence and survival in mammalian hosts

L Romani, F Bistoni, P Puccetti - Current opinion in microbiology, 2003 - Elsevier
Although morphological flexibility could be a key contributor to fungal virulence, no
molecular data has unambiguously established fungal morphogenesis as a virulence factor …

Morphogenesis in Candida albicans

M Whiteway, C Bachewich - Annu. Rev. Microbiol., 2007 - annualreviews.org
Candida albicans is termed a dimorphic fungus because it proliferates in either a yeast form
or a hyphal form. The switch between these forms is the result of a complex interplay of …

Transcriptional control of hyphal morphogenesis in Candida albicans

S Villa, M Hamideh, A Weinstock, MN Qasim… - FEMS yeast …, 2020 - academic.oup.com
Candida albicans is a multimorphic commensal organism and opportunistic fungal pathogen
in humans. A morphological switch between unicellular budding yeast and multicellular …