Importance Low-dose aspirin has been widely used for primary and secondary prevention of
stroke. The balance between potential reduction of ischemic stroke events and increased …

Background Aspirin is a well-established therapy for the secondary prevention of
cardiovascular events. However, its role in the primary prevention of cardiovascular disease …

Rationale Aspirin has positive and negative effects on a number of age-related chronic
conditions and there is uncertainty regarding its role in primary prevention in people aged …

Importance Use of low-dose aspirin for the primary prevention of cardiovascular events
remains controversial because increased risk of bleeding may offset the overall benefit …

Background Low-dose aspirin has proven effectiveness in secondary and primary
prevention of cardiovascular events, but is also associated with an increased risk of major …

Background Aspirin therapy reduces stroke by about 25% for persons with atherosclerotic
vascular disease, but the effect in those without clinically apparent vascular disease is …

Importance Prevention of atherosclerotic cardiovascular diseases is an important public
health priority in Japan due to an aging population. Objective To determine whether daily …

Background Information on the use of aspirin to increase healthy independent life span in
older persons is limited. Whether 5 years of daily low-dose aspirin therapy would extend …

Low-dose aspirin (acetylsalicylic acid) therapy has been shown to reduce the risk of
vascular events and there is increasing evidence of its potential to reduce the rate of …

Context.—Aspirin has been widely used to prevent myocardial infarction and ischemic
stroke but some studies have suggested it increases risk of hemorrhagic stroke. Objective …