The role of epigenetics in primary biliary cholangitis
Primary Biliary Cholangitis (PBC) is a rare autoimmune disease of the liver, affecting mostly
females. There is evidence that epigenetic changes have a pathogenic role in PBC …
females. There is evidence that epigenetic changes have a pathogenic role in PBC …
Epigenetics and primary biliary cirrhosis: a comprehensive review and implications for autoimmunity
YQ Xie, HD Ma, ZX Lian - Clinical reviews in allergy & immunology, 2016 - Springer
Primary biliary cirrhosis (PBC) is a chronic inflammatory autoimmune disease that develops
based upon the interaction of genetic and environmental factors. Recent genome-wide …
based upon the interaction of genetic and environmental factors. Recent genome-wide …
Epigenetics of primary biliary cholangitis
Y Li, R Tang, X Ma - Epigenetics in Allergy and Autoimmunity, 2020 - Springer
Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease with non-suppurative
destruction of the intrahepatic bile ducts. The interplay of genetics and environmental …
destruction of the intrahepatic bile ducts. The interplay of genetics and environmental …
The immunobiology of female predominance in primary biliary cholangitis
Primary biliary cholangitis (PBC) is an autoimmune liver disease with a striking female
preponderance. The mechanisms behind this predominance are still to be elucidated …
preponderance. The mechanisms behind this predominance are still to be elucidated …
Epigenetic investigation of variably X chromosome inactivated genes in monozygotic female twins discordant for primary biliary cirrhosis
MM Mitchell, A Lleo, L Zammataro, MJ Mayo… - Epigenetics, 2011 - Taylor & Francis
Primary biliary cirrhosis (PBC) is an autoimmune chronic cholestatic liver disease with a
strong genetic susceptibility due to the high concordance in monozygotic (MZ) twins and a …
strong genetic susceptibility due to the high concordance in monozygotic (MZ) twins and a …
The epigenetics of PBC: the link between genetic susceptibility and environment
Primary biliary cholangitis (PBC) previously known as primary biliary cirrhosis is an
autoimmune disease-associated with progressive cholestasis, the presence of autoreactive …
autoimmune disease-associated with progressive cholestasis, the presence of autoreactive …
The genetics and epigenetics of primary biliary cholangitis
A Tanaka, PSC Leung, ME Gershwin - Clinics in liver disease, 2018 - liver.theclinics.com
Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease; it is an autoimmune
reaction targeted to intrahepatic biliary epithelial cells (BECs), eventually resulting in …
reaction targeted to intrahepatic biliary epithelial cells (BECs), eventually resulting in …
Genetics and epigenetics in the pathogenesis of primary biliary cholangitis
Primary biliary cholangitis (PBC) is a chronic, slowly progressive cholestatic autoimmune
liver disease predominantly afflicting women. PBC is characterized by the presence of …
liver disease predominantly afflicting women. PBC is characterized by the presence of …
Primary biliary cirrhosis: does X mark the spot?
Primary biliary cirrhosis (PBC) is an autoimmune disease of unknown etiology leading to
progressive destruction of intrahepatic bile duct, with cholestasis, cirrhosis, and eventually …
progressive destruction of intrahepatic bile duct, with cholestasis, cirrhosis, and eventually …
The genetic architecture of primary biliary cholangitis
Primary biliary cholangitis (PBC) is a rare autoimmune disease of the liver affecting the small
bile ducts. From a genetic point of view, PBC is a complex trait and several genetic and …
bile ducts. From a genetic point of view, PBC is a complex trait and several genetic and …