[HTML][HTML] The fate of chemoresistance in triple negative breast cancer (TNBC)
EA O'Reilly, L Gubbins, S Sharma, R Tully, MHZ Guang… - BBA clinical, 2015 - Elsevier
Background Treatment options for women presenting with triple negative breast cancer
(TNBC) are limited due to the lack of a therapeutic target and as a result, are managed with …
(TNBC) are limited due to the lack of a therapeutic target and as a result, are managed with …
[HTML][HTML] Mechanisms of chemotherapy resistance in triple-negative breast cancer—how we can rise to the challenge
M Nedeljković, A Damjanović - Cells, 2019 - mdpi.com
Triple-negative (TNBC) is the most lethal subtype of breast cancer owing to high
heterogeneity, aggressive nature, and lack of treatment options. Chemotherapy remains the …
heterogeneity, aggressive nature, and lack of treatment options. Chemotherapy remains the …
An insight into the cancer stem cell survival pathways involved in chemoresistance in triple-negative breast cancer
Triple-negative breast cancer (TNBC) is the most complex, aggressive and fatal subtype of
breast cancer. Owing to the lack of targeted therapy and heterogenic nature of TNBC …
breast cancer. Owing to the lack of targeted therapy and heterogenic nature of TNBC …
[HTML][HTML] Triple negative breast cancer: a mountain yet to be scaled despite the triumphs
Q Wu, S Siddharth, D Sharma - Cancers, 2021 - mdpi.com
Simple Summary Triple-negative breast cancer (TNBC) is a highly aggressive subtype of
breast cancer that cannot be treated with endocrine therapy and Her2-targeted therapy …
breast cancer that cannot be treated with endocrine therapy and Her2-targeted therapy …
[HTML][HTML] Challenges for triple negative breast cancer treatment: defeating heterogeneity and cancer stemness
R Mahmoud, P Ordóñez-Morán, C Allegrucci - Cancers, 2022 - mdpi.com
Simple Summary Triple Negative Breast Cancer represents a cancer type with an unmet
clinical need. This type of breast cancer presents the worse clinical outcome due to its …
clinical need. This type of breast cancer presents the worse clinical outcome due to its …
[HTML][HTML] Senescence-induced chemoresistance in triple negative breast cancer and evolution-based treatment strategies
Triple negative breast cancer (TNBC) is classically treated with combination
chemotherapies. Although, initially responsive to chemotherapies, TNBC patients frequently …
chemotherapies. Although, initially responsive to chemotherapies, TNBC patients frequently …
Triple-negative breast cancer therapeutic resistance: Where is the Achilles' heel?
Triple-negative breast cancer (TNBC) shows a higher response rate to systemic therapy
compared with other breast cancer subtypes. However, the tumor differentiation of TNBC is …
compared with other breast cancer subtypes. However, the tumor differentiation of TNBC is …
[HTML][HTML] Practical classification of triple-negative breast cancer: intratumoral heterogeneity, mechanisms of drug resistance, and novel therapies
A Marra, D Trapani, G Viale, C Criscitiello… - NPJ breast …, 2020 - nature.com
Triple-negative breast cancer (TNBC) is not a unique disease, encompassing multiple
entities with marked histopathological, transcriptomic and genomic heterogeneity. Despite …
entities with marked histopathological, transcriptomic and genomic heterogeneity. Despite …
Mechanisms of resistance of chemotherapy in early-stage triple negative breast cancer (TNBC)
L Wein, S Loi - The Breast, 2017 - Elsevier
Triple negative breast cancer (TNBC) a clinically aggressive subtype of breast cancer with
poor outcomes. Chromosomal instability is a hallmark of many TNBCs, and likely underlies …
poor outcomes. Chromosomal instability is a hallmark of many TNBCs, and likely underlies …
Identification and use of biomarkers in treatment strategies for triple‐negative breast cancer subtypes
BD Lehmann, JA Pietenpol - The Journal of pathology, 2014 - Wiley Online Library
Triple‐negative breast cancer (TNBC) is a heterogeneous disease with distinct molecular
subtypes that respond differentially to chemotherapy and targeted agents. The absence of …
subtypes that respond differentially to chemotherapy and targeted agents. The absence of …
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- breast cancer achilles heel
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- breast cancer drug resistance