No room to breathe: the importance of lung hyperinflation in COPD

M Thomas, M Decramer, DE O'Donnell - Primary Care Respiratory …, 2013 - nature.com
Patients with chronic obstructive pulmonary disease (COPD) are progressively limited in
their ability to undertake normal everyday activities by a combination of exertional dyspnoea …

The clinical importance of dynamic lung hyperinflation in COPD

DE O'Donnell, P Laveneziana - COPD: Journal of Chronic …, 2006 - Taylor & Francis
Lung hyperinflation commonly accompanies expiratory flow-limitation in patients with
Chronic Obstructive Pulmonary Disease (COPD) and contributes importantly to dyspnea and …

New physiological insights into dyspnea and exercise intolerance in chronic obstructive pulmonary disease patients

P Laveneziana, JA Guenette, KA Webb… - Expert review of …, 2012 - Taylor & Francis
Dyspnea and reduced exercise tolerance are common consequences of chronic obstructive
pulmonary disease (COPD) and contribute importantly to poor perceived health status …

Physiology and consequences of lung hyperinflation in COPD

DE O'donnell, P Laveneziana - European Respiratory Review, 2006 - Eur Respiratory Soc
Lung hyperinflation commonly accompanies expiratory flow limitation in patients with
chronic obstructive pulmonary disease (COPD) and contributes importantly to morbidity and …

[HTML][HTML] Mechanisms, assessment and therapeutic implications of lung hyperinflation in COPD

A Rossi, Z Aisanov, S Avdeev, G Di Maria… - Respiratory …, 2015 - Elsevier
The main complaint of patients with chronic obstructive pulmonary disease (COPD) is
shortness of breath with exercise, that is usually progressive. The principal mechanism that …

Lung hyperinflation in COPD: applying physiology to clinical practice

DE O'Donnell, KA Webb, JA Neder - COPD Research and Practice, 2015 - Springer
In chronic obstructive pulmonary disease (COPD), worsening expiratory flow limitation
together with alteration in the elastic properties of the lung are associated with progressive …

Hyperinflation and its management in COPD

L Puente-Maestu, WW Stringer - International journal of chronic …, 2006 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is characterized by poorly reversible airflow
limitation. The pathological hallmarks of COPD are inflammation of the peripheral airways …

Pathogenesis of hyperinflation in chronic obstructive pulmonary disease

P Gagnon, JA Guenette, D Langer… - … journal of chronic …, 2014 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD) is a preventable and treatable lung disease
characterized by airflow limitation that is not fully reversible. In a significant proportion of …

Lung hyperinflation in chronic obstructive pulmonary disease: mechanisms, clinical implications and treatment

D Langer, CE Ciavaglia, JA Neder… - Expert review of …, 2014 - Taylor & Francis
Lung hyperinflation is highly prevalent in patients with chronic obstructive pulmonary
disease and occurs across the continuum of the disease. A growing body of evidence …

The major limitation to exercise performance in COPD is dynamic hyperinflation

DE O'Donnell, KA Webb - Journal of applied physiology, 2008 - journals.physiology.org
The inability to engage in sustained physical activity is a common feature of chronic
obstructive pulmonary disease (COPD) and contributes importantly to the perception of poor …