Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons: involvement of glucocorticoid secretion and excitatory amino acid receptors

AM Magarin, BS McEwen - Neuroscience, 1995 - Elsevier
Repeated restraint stress of rats for 21 days causes atrophy of apical dendrites of
hippocampal CA3c pyramidal neurons. This effect is mimicked by daily corticosterone …

Stress-induced atrophy of apical dendrites of hippocampal CA3c neurons: comparison of stressors

AM Magarin, BS McEwen - Neuroscience, 1995 - Elsevier
Repeated restraint stress induces an atrophy of apical dendrites of CA3c pyramidal neurons
in the hippocampus, but the relationship between stress and adrenocortical activation has …

Stress induces atrophy of apical dendrites of hippocampal CA3 pyramidal neurons

Y Watanabe, E Gould, BS McEwen - Brain research, 1992 - Elsevier
The hippocampus is vulnerable to the damaging actions of insults such as transient
ischemia and repetitive stimulation, as well as repeated exposure to exogenous …

Morphological changes in the hippocampal CA3 region induced by non-invasive glucocorticoid administration: a paradox

AM Magariños, M Orchinik, BS McEwen - Brain research, 1998 - Elsevier
Repeated stress induces atrophy, or remodeling, of apical dendrites in hippocampal CA3
pyramidal neurons. In rats, the stress effect is blocked by adrenal steroid synthesis inhibitors …

Phenytoin prevents stress‐and corticosterone‐induced atrophy of CA3 pyramidal neurons

Y Watanabe, E Gould, HA Cameron, DC Daniels… - …, 1992 - Wiley Online Library
Repeated daily restraint stress and daily corticosterone administration to adult male
Sprague‐Dawley rats leads to decreases in the number of branch points and length of …

Effects of antidepressants and benzodiazepine treatments on the dendritic structure of CA3 pyramidal neurons after chronic stress

AM Magariños, A Deslandes, BS McEwen - European journal of …, 1999 - Elsevier
Both repeated stress and corticosterone administration induce remodeling of apical
dendrites of hippocampal CA3 pyramidal neurons. Circulating glucocorticoids are involved …

Reorganization of the morphology of hippocampal neurites and synapses after stress-induced damage correlates with behavioral improvement

N Sousa, NV Lukoyanov, MD Madeira, OFX Almeida… - Neuroscience, 2000 - Elsevier
We recently demonstrated that stress-induced cognitive deficits in rats do not correlate with
hippocampal neuronal loss. Working on the premise that subtle structural changes may …

Sex differences in dendritic atrophy of CA3 pyramidal neurons in response to chronic restraint stress

LAM Galea, BS McEwen, P Tanapat, T Deak… - Neuroscience, 1997 - Elsevier
The present study investigated the effects of 21 days of chronic restraint stress on neural and
endocrine parameters in male and female rats. Consistent with previous results, repeated …

Chronic stress-induced hippocampal vulnerability: the glucocorticoid vulnerability hypothesis

CD Conrad - Reviews in the Neurosciences, 2008 - degruyter.com
The hippocampus, a limbic structure important in learning and memory, is particularly
sensitive to chronic stress and to glucocorticoids. While glucocorticoids are essential for an …

Stress and the brain: a paradoxical role for adrenal steroids

BS Mcewen, D Albeck, H Cameron, HM Chao… - Vitamins & …, 1995 - Elsevier
Publisher Summary This chapter discusses paradoxical effects of adrenal steroids in the
hippocampus. Stress is common in everyday life and is blamed for many problems. There is …