A comprehensive review of autophagy and its various roles in infectious, non-infectious, and lifestyle diseases: current knowledge and prospects for disease …

R Khandia, M Dadar, A Munjal, K Dhama, K Karthik… - Cells, 2019 - mdpi.com
Autophagy (self-eating) is a conserved cellular degradation process that plays important
roles in maintaining homeostasis and preventing nutritional, metabolic, and infection …

The emerging roles of autophagy in human diseases

Y Lei, DJ Klionsky - Biomedicines, 2021 - mdpi.com
Autophagy, a process of cellular self-digestion, delivers intracellular components including
superfluous and dysfunctional proteins and organelles to the lysosome for degradation and …

[HTML][HTML] Autophagy in the pathogenesis of disease

B Levine, G Kroemer - Cell, 2008 - cell.com
Autophagy is a lysosomal degradation pathway that is essential for survival, differentiation,
development, and homeostasis. Autophagy principally serves an adaptive role to protect …

Autophagy in health and disease: From molecular mechanisms to therapeutic target

G Lu, Y Wang, Y Shi, Z Zhang, C Huang, W He… - MedComm, 2022 - Wiley Online Library
Macroautophagy/autophagy is an evolutionally conserved catabolic process in which
cytosolic contents, such as aggregated proteins, dysfunctional organelle, or invading …

Targeting autophagy to overcome human diseases

M Condello, E Pellegrini, M Caraglia… - International journal of …, 2019 - mdpi.com
Autophagy is an evolutionarily conserved cellular process, through which damaged
organelles and superfluous proteins are degraded, for maintaining the correct cellular …

Autophagy: supporting cellular and organismal homeostasis by self-eating

EL Eskelinen - The international journal of biochemistry & cell biology, 2019 - Elsevier
Autophagy is a conserved catabolic process that delivers cytoplasmic components and
organelles to lysosomes for degradation and recycling. This pathway serves to degrade …

Autophagy in human health and disease

AMK Choi, SW Ryter, B Levine - New England Journal of …, 2013 - Mass Medical Soc
Autophagy in Human Health and Disease | New England Journal of Medicine Skip to main
content The New England Journal of Medicine homepage Advanced Search SEARCH …

Emerging role of selective autophagy in human diseases

K Mizumura, AMK Choi, SW Ryter - Frontiers in pharmacology, 2014 - frontiersin.org
Autophagy was originally described as a highly conserved system for the degradation of
cytosol through a lysosome-dependent pathway. In response to starvation, autophagy …

Therapeutic implications of autophagy inducers in immunological disorders, infection, and cancer

S Byun, E Lee, KW Lee - International journal of molecular sciences, 2017 - mdpi.com
Autophagy is an essential catabolic program that forms part of the stress response and
enables cells to break down their own intracellular components within lysosomes for …

Therapeutic modulation of autophagy: which disease comes first?

MC Maiuri, G Kroemer - Cell Death & Differentiation, 2019 - nature.com
The relentless efforts of thousands of researchers have allowed deciphering the molecular
machinery that regulates and executes autophagy, thus identifying multiple molecular …