Cross-neutralization of four paramyxoviruses by a human monoclonal antibody
Broadly neutralizing antibodies reactive against most and even all variants of the same viral
species have been described for influenza and HIV-1 (ref.). However, whether a neutralizing …
species have been described for influenza and HIV-1 (ref.). However, whether a neutralizing …
Structural basis for antibody cross-neutralization of respiratory syncytial virus and human metapneumovirus
Respiratory syncytial virus (RSV) and human metapneumovirus (HMPV) are two closely
related viruses that cause bronchiolitis and pneumonia in infants and the elderly 1, with a …
related viruses that cause bronchiolitis and pneumonia in infants and the elderly 1, with a …
Engineering, structure and immunogenicity of the human metapneumovirus F protein in the postfusion conformation
V Más, L Rodriguez, E Olmedillas, O Cano… - PLoS …, 2016 - journals.plos.org
Human metapneumovirus (hMPV) is a paramyxovirus that is a common cause of
bronchiolitis and pneumonia in children less than five years of age. The hMPV fusion (F) …
bronchiolitis and pneumonia in children less than five years of age. The hMPV fusion (F) …
Isolation and characterization of monoclonal antibodies which neutralize human metapneumovirus in vitro and in vivo
ND Ulbrandt, H Ji, NK Patel, JM Riggs… - Journal of …, 2006 - Am Soc Microbiol
Human metapneumovirus (hMPV) is a recently described member of the Paramyxoviridae
family/Pneumovirinae subfamily and shares many common features with respiratory …
family/Pneumovirinae subfamily and shares many common features with respiratory …
[HTML][HTML] Individual contributions of the human metapneumovirus F, G, and SH surface glycoproteins to the induction of neutralizing antibodies and protective immunity
MH Skiadopoulos, S Biacchesi, UJ Buchholz… - Virology, 2006 - Elsevier
We evaluated the individual contributions of the three surface glycoproteins of human
metapneumovirus (HMPV), namely the fusion F, attachment G, and small hydrophobic SH …
metapneumovirus (HMPV), namely the fusion F, attachment G, and small hydrophobic SH …
The two major human metapneumovirus genetic lineages are highly related antigenically, and the fusion (F) protein is a major contributor to this antigenic relatedness
MH Skiadopoulos, S Biacchesi, UJ Buchholz… - Journal of …, 2004 - Am Soc Microbiol
The growth properties and antigenic relatedness of the CAN98-75 (CAN75) and the CAN97-
83 (CAN83) human metapneumovirus (HMPV) strains, which represent the two distinct …
83 (CAN83) human metapneumovirus (HMPV) strains, which represent the two distinct …
In vivo and in vitro escape from neutralizing antibodies 2G12, 2F5, and 4E10
A Manrique, P Rusert, B Joos, M Fischer… - Journal of …, 2007 - Am Soc Microbiol
Recently, passive immunization of human immunodeficiency virus (HIV)-infected individuals
with monoclonal antibodies (MAbs) 2G12, 2F5, and 4E10 provided evidence of the in vivo …
with monoclonal antibodies (MAbs) 2G12, 2F5, and 4E10 provided evidence of the in vivo …
The immune response to human metapneumovirus is associated with aberrant immunity and impaired virus clearance in BALB/c mice
R Alvarez, RA Tripp - Journal of virology, 2005 - Am Soc Microbiol
Human metapneumovirus (HMPV), recently identified in isolates from children hospitalized
with acute respiratory tract illness, is associated with clinical diagnosis of pneumonia …
with acute respiratory tract illness, is associated with clinical diagnosis of pneumonia …
Immunization of macaques with formalin-inactivated human metapneumovirus induces hypersensitivity to hMPV infection
RL de Swart, BG van den Hoogen, T Kuiken, S Herfst… - Vaccine, 2007 - Elsevier
Human metapneumovirus (hMPV), a member of the family Paramyxoviridae, is an important
cause of acute respiratory tract disease. In the 1960s, vaccination with formalin-inactivated …
cause of acute respiratory tract disease. In the 1960s, vaccination with formalin-inactivated …
Infection of nonhuman primates with recombinant human metapneumovirus lacking the SH, G, or M2-2 protein categorizes each as a nonessential accessory protein …
S Biacchesi, QN Pham, MH Skiadopoulos… - Journal of …, 2005 - Am Soc Microbiol
Recombinant human metapneumovirus (HMPV) in which the SH, G, or M2 gene or open
reading frame was deleted by reverse genetics was evaluated for replication and vaccine …
reading frame was deleted by reverse genetics was evaluated for replication and vaccine …