Identification of common variants associated with human hippocampal and intracranial volumes

JL Stein, SE Medland, AA Vasquez, DP Hibar… - Nature …, 2012 - nature.com
Identifying genetic variants influencing human brain structures may reveal new biological
mechanisms underlying cognition and neuropsychiatric illness. The volume of the …

Common variants at 12q14 and 12q24 are associated with hippocampal volume

Nature genetics, 2012 - nature.com
Aging is associated with reductions in hippocampal volume that are accelerated by
Alzheimer's disease and vascular risk factors. Our genome-wide association study (GWAS) …

Genome-wide association analysis of 19,629 individuals identifies variants influencing regional brain volumes and refines their genetic co-architecture with cognitive …

B Zhao, T Luo, T Li, Y Li, J Zhang, Y Shan, X Wang… - Nature …, 2019 - nature.com
Volumetric variations of the human brain are heritable and are associated with many brain-
related complex traits. Here we performed genome-wide association studies (GWAS) of 101 …

Common genetic variants influence human subcortical brain structures

DP Hibar, JL Stein, ME Renteria, A Arias-Vasquez… - Nature, 2015 - nature.com
The highly complex structure of the human brain is strongly shaped by genetic influences.
Subcortical brain regions form circuits with cortical areas to coordinate movement, learning …

[HTML][HTML] Novel genetic loci associated with hippocampal volume

DP Hibar, HHH Adams, N Jahanshad… - Nature …, 2017 - nature.com
The hippocampal formation is a brain structure integrally involved in episodic memory,
spatial navigation, cognition and stress responsiveness. Structural abnormalities in …

Common variants at 6q22 and 17q21 are associated with intracranial volume

Nature genetics, 2012 - nature.com
During aging, intracranial volume remains unchanged and represents maximally attained
brain size, while various interacting biological phenomena lead to brain volume loss …

[HTML][HTML] Genome-wide association studies of brain imaging phenotypes in UK Biobank

LT Elliott, K Sharp, F Alfaro-Almagro, S Shi, KL Miller… - Nature, 2018 - nature.com
The genetic architecture of brain structure and function is largely unknown. To investigate
this, we carried out genome-wide association studies of 3,144 functional and structural brain …

[HTML][HTML] The genetic architecture of the human thalamus and its overlap with ten common brain disorders

T Elvsåshagen, A Shadrin, O Frei… - Nature …, 2021 - nature.com
The thalamus is a vital communication hub in the center of the brain and consists of distinct
nuclei critical for consciousness and higher-order cortical functions. Structural and functional …

A common variant of HMGA2 is associated with adult and childhood height in the general population

MN Weedon, G Lettre, RM Freathy, CM Lindgren… - Nature …, 2007 - nature.com
Human height is a classic, highly heritable quantitative trait. To begin to identify genetic
variants influencing height, we examined genome-wide association data from 4,921 …

Genetic architecture of subcortical brain structures in 38,851 individuals

CL Satizabal, HHH Adams, DP Hibar, CC White… - Nature …, 2019 - nature.com
Subcortical brain structures are integral to motion, consciousness, emotions and learning.
We identified common genetic variation related to the volumes of the nucleus accumbens …