Identification of common variants associated with human hippocampal and intracranial volumes
Identifying genetic variants influencing human brain structures may reveal new biological
mechanisms underlying cognition and neuropsychiatric illness. The volume of the …
mechanisms underlying cognition and neuropsychiatric illness. The volume of the …
Common variants at 12q14 and 12q24 are associated with hippocampal volume
Nature genetics, 2012 - nature.com
Aging is associated with reductions in hippocampal volume that are accelerated by
Alzheimer's disease and vascular risk factors. Our genome-wide association study (GWAS) …
Alzheimer's disease and vascular risk factors. Our genome-wide association study (GWAS) …
Genome-wide association analysis of 19,629 individuals identifies variants influencing regional brain volumes and refines their genetic co-architecture with cognitive …
Volumetric variations of the human brain are heritable and are associated with many brain-
related complex traits. Here we performed genome-wide association studies (GWAS) of 101 …
related complex traits. Here we performed genome-wide association studies (GWAS) of 101 …
Common genetic variants influence human subcortical brain structures
The highly complex structure of the human brain is strongly shaped by genetic influences.
Subcortical brain regions form circuits with cortical areas to coordinate movement, learning …
Subcortical brain regions form circuits with cortical areas to coordinate movement, learning …
[HTML][HTML] Novel genetic loci associated with hippocampal volume
The hippocampal formation is a brain structure integrally involved in episodic memory,
spatial navigation, cognition and stress responsiveness. Structural abnormalities in …
spatial navigation, cognition and stress responsiveness. Structural abnormalities in …
Common variants at 6q22 and 17q21 are associated with intracranial volume
Nature genetics, 2012 - nature.com
During aging, intracranial volume remains unchanged and represents maximally attained
brain size, while various interacting biological phenomena lead to brain volume loss …
brain size, while various interacting biological phenomena lead to brain volume loss …
[HTML][HTML] Genome-wide association studies of brain imaging phenotypes in UK Biobank
The genetic architecture of brain structure and function is largely unknown. To investigate
this, we carried out genome-wide association studies of 3,144 functional and structural brain …
this, we carried out genome-wide association studies of 3,144 functional and structural brain …
[HTML][HTML] The genetic architecture of the human thalamus and its overlap with ten common brain disorders
T Elvsåshagen, A Shadrin, O Frei… - Nature …, 2021 - nature.com
The thalamus is a vital communication hub in the center of the brain and consists of distinct
nuclei critical for consciousness and higher-order cortical functions. Structural and functional …
nuclei critical for consciousness and higher-order cortical functions. Structural and functional …
A common variant of HMGA2 is associated with adult and childhood height in the general population
Human height is a classic, highly heritable quantitative trait. To begin to identify genetic
variants influencing height, we examined genome-wide association data from 4,921 …
variants influencing height, we examined genome-wide association data from 4,921 …
Genetic architecture of subcortical brain structures in 38,851 individuals
Subcortical brain structures are integral to motion, consciousness, emotions and learning.
We identified common genetic variation related to the volumes of the nucleus accumbens …
We identified common genetic variation related to the volumes of the nucleus accumbens …