Abstract Background Trehalose-6-phosphate phosphatase (TPP6) is a key enzyme in the
trehalose biosynthesis pathway. The accumulation of TPP6 inside the body is harmful to the …

Trehalose phosphate synthase (TPS), a key enzyme in trehalose synthesis, is not present in
mammals but critical to the viability of a wide range of lower organisms. However, almost …

Serine/threonine-protein phosphatases (STPs), as integral constituents of parasitic
excretory/secretory proteins, are assumed to be released during the host–parasite …

As opposed to organism-based drug screening approaches, protein-based strategies have
the distinct advantage of providing insights into the molecular mechanisms of chemical …

The pleiotropic functions of disaccharide trehalose in the biology of nematodes and its
absence from mammalian cells suggest that its biosynthesis may provide a useful target for …

Background Histidine acid phosphatase (HAP), a member of the histidine phosphatase
superfamily, is widely found in parasites and is also a potential vaccine antigen or drug …

Biotin lipoyl attachment and 2‐oxoacid dehydrogenase acyltransferase (BLAODA), as an
essential excretion of Haemonchus contortus (HcESPs), was identified to have antigenic …

Trehalose 6-phosphate (T6P) synthase (TPS; EC 2.4. 1.15) was isolated from muscles of
Ascaris suum by ammonium sulphate fractionation, ion-exchange DEAE SEPHACELTM …

Abstract Trehalose-6-phosphate synthase (TPS) is responsible for synthesizing trehalose,
which is prevalent in crustaceans and insects as blood-sugar. In this paper, a TPS gene from …

Background The trehalose synthetic pathway is present in bacteria, fungi, plants and
invertebrate animals, but is absent in vertebrates. This disaccharide mainly functions as a …