Polyunsaturated fatty acids (PUFA) are fundamental building materials for cells and play
crucial function as signaling molecules. When PUFA are used as substrates for non …

The maintenance of redox homeostasis is associated with a healthy status while the
disruption of this mechanism leads to the development of various pathological conditions …

Short-chain fatty acids (SCFAs), produced by colonic bacteria and obtained from the diet,
have been linked to beneficial effects on human health associated with their metabolic and …

The transcription factor NRF2 and its endogenous inhibitor KEAP1 play a crucial role in the
maintenance of cellular redox homeostasis by regulating the gene expression of diverse …

Diets replete with n− 3 PUFAs (polyunsaturated fatty acids) are known to have therapeutic
potential for the heart, although a specifically defined duration of the n− 3 PUFA diet …

The NF-E2-related factor 2 (Nrf2)-mediated signalling pathway provides living organisms an
efficient and pivotal line of defensive to counteract environmental insults and endogenous …

Consumption of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) can
mitigate the progression of diseases in which oxidative stress represents a common …

The overconsumption of both saturated fats and fructose in the modern society has been
related to the development of nonalcoholic fatty liver disease (NAFLD). However, the …

Highlights•Formation of nitro-fatty acids.•Signaling of nitro-fatty acids.•Anti-fibrotic effects of
nitro-fatty acids.Fatty acids not only provide caloric energy in our diets and building blocks of …

Oxidative stress can induce occurrence of non-alcoholic fatty liver disease (NAFLD). Nrf2 is
a central regulator of cellular oxidative stress and also participates in the control of lipid …