Anatomically and physiologically informed computational model of hepatic contrast perfusion for virtual imaging trials

TJ Sauer, E Abadi, P Segars, E Samei - Medical physics, 2022 - Wiley Online Library
Purpose Virtual (in silico) imaging trials (VITs), involving computerized phantoms and
models of the imaging process, provide a modern alternative to clinical imaging trials. VITs …

Anatomically-and computationally-informed hepatic contrast perfusion simulations for use in virtual clinical trials

TJ Sauer, E Abadi, P Segars… - Medical Imaging 2019 …, 2019 - spiedigitallibrary.org
This study modeled a framework for virtual human liver phantoms, focusing primarily on the
intricate vascular networks that comprise the liver. Large vasculature was segmented from …

Virtual clinical trials in medical imaging: a review

E Abadi, WP Segars, BMW Tsui… - Journal of Medical …, 2020 - spiedigitallibrary.org
The accelerating complexity and variety of medical imaging devices and methods have
outpaced the ability to evaluate and optimize their design and clinical use. This is a …

Virtual parenchymal perfusion for selective intra-arterial therapy of liver cancer

D Lesage, G Pizaine, S Miyayama… - 2016 IEEE 13th …, 2016 - ieeexplore.ieee.org
Intra-arterial injection of therapeutic agents is among the most common options for
unresectable liver cancer. Such procedures rely on an in-depth assessment of the vessels …

Computation of contrast-enhanced perfusion using only two CT scan phases: a proof-of-concept study on abdominal organs

M Cressoni, A Cozzi, S Schiaffino, P Cadringher… - European Radiology …, 2022 - Springer
Background Computed tomography perfusion imaging (CTPI) by repeated scanning has
clinical relevance but implies relatively high radiation exposure. We present a method to …

Low-dose CT perfusion of the liver using reconstruction of difference

S Seyyedi, E Liapi, T Lasser, R Ivkov… - IEEE transactions on …, 2018 - ieeexplore.ieee.org
Liver CT perfusion (CTP) is used in the detection, staging, and treatment response analysis
of hepatic diseases. Unfortunately, CTP radiation exposures are significant, limiting more …

Virtual imaging trials: An emerging experimental paradigm in imaging research and practice

E Samei, E Abadi, A Kapadia, J Lo… - … 2020: Physics of …, 2020 - spiedigitallibrary.org
As medical imaging technologies continue to accelerate in complexity, application, and
multiplicity of design choices and use features, they should ideally be evaluated and …

Development of a fast, voxel-based, and scanner-specific CT simulator for image-quality-based virtual clinical trials

E Abadi, B Harrawood, A Kapadia… - … 2018: Physics of …, 2018 - spiedigitallibrary.org
This study aimed to develop a simulation framework to synthesize accurate and scanner-
specific Computed Tomography (CT) images of voxel-based computational phantoms. Two …

The effect of contrast material on radiation dose at CT: Part I. Incorporation of contrast material dynamics in anthropomorphic phantoms

P Sahbaee, WP Segars, D Marin, RC Nelson, E Samei - Radiology, 2017 - pubs.rsna.org
Purpose To develop a method to incorporate the propagation of contrast material into
computational anthropomorphic phantoms for estimation of organ dose at computed …

Porcine ex vivo liver phantom for dynamic contrast-enhanced computed tomography: development and initial results

SM Thompson, JC Ramirez-Giraldo… - Investigative …, 2011 - journals.lww.com
Objectives: To demonstrate the feasibility of developing a fixed, dual-input, biologic liver
phantom for dynamic contrast-enhanced computed tomography (CT) imaging and to report …