Pulmonary arterial hypertension (PAH) is a chronic disease with poor prognosis and
important exercise limitation despite the proliferation of treatment options in the last decade …

Pulmonary arterial hypertension (PAH) is associated with symptoms of dyspnea and fatigue,
which contribute to exercise limitation. The origins and significance of dyspnea and fatigue …

Exercise intolerance is a cardinal symptom of pulmonary arterial hypertension (PAH) and
strongly impacts patients9 quality of life (QoL). Although central cardiopulmonary …

The lungs are the only organ that receives the entire cardiac output with every stroke. The
pulmonary circulation is normally a high-flow, low-resistance, low-pressure system that …

Survival in patients with pulmonary arterial hypertension (PAH) is determined by right
ventricular (RV) function adaptation to afterload. How altered RV function impacts on …

Objective Inadequate right ventricular (RV) and pulmonary arterial (PA) functional responses
to exercise are important yet poorly understood features of pulmonary arterial hypertension …

Background—Right ventricular (RV) functional reserve affects functional capacity and
prognosis in patients with pulmonary arterial hypertension (PAH). PAH associated with …

Exercise intolerance and right ventricular (RV) dysfunction are cardinal features of
pulmonary arterial hypertension (PAH). Despite the significantly elevated afterload, patients …

Pulmonary arterial hypertension (PAH) is an obstructive pulmonary vasculopathy,
characterized by excess proliferation, apoptosis resistance, inflammation, fibrosis, and …

Pulmonary arterial hypertension (PAH) is characterized by a continuous increase in pre-
capillary pulmonary vascular resistance (PVR) with a progressive reduction of cardiac output …