Postsurgical treatment of glioblastoma multiforme (GBM) by systemic chemotherapy and
radiotherapy is often inefficient. Tumor cells infiltrating deeply into the brain parenchyma are …

Intratumoral drug delivery is a promising approach for the treatment of glioblastoma
multiforme (GBM). However, drug washout remains a major challenge in GBM therapy. Our …

Glioblastoma multiforme (GBM) is a devastating tumor of the central nervous system,
currently missing an effective treatment. The therapeutic gold standard consists of surgical …

Immunotherapies have revolutionized intervention strategies for many primary cancers, but
have not improved the outcomes of glioblastoma multiforme (GBM), which remains one of …

Glioblastoma (GBM) treatment includes, when possible, surgical resection of the tumor
followed by radiotherapy and oral chemotherapy with temozolomide, however recurrences …

To date, the delivery of therapeutic agents for malignant brain tumors (such as glioblastoma
multiforme (GBM)) remains a significant obstacle due to the existence of the blood–brain …

A major obstacle to the management of malignant glioma is the inability to effectively deliver
therapeutic agent to the tumor. In this study, we describe a polymeric nanoparticle vector that …

Graphene oxide (GO) nanoparticles have been developed for a variety of biomedical
applications as a number of different therapeutic modalities may be added onto them. Here …

Patients with glioblastoma multiforme (GBM), the most common primary brain tumor in
adults, have still a poor prognosis though new strategies of radio-and chemotherapy have …

Chemotherapy is commonly associated with limited effectiveness and unwanted side effects
in normal cells and tissues, due to the lack of specificity of therapeutic agents to cancer cells …