The global ascendency of OXA-48-type carbapenemases

JDD Pitout, G Peirano, MM Kock… - Clinical microbiology …, 2019 - Am Soc Microbiol
Surveillance studies have shown that OXA-48-like carbapenemases are the most common
carbapenemases in Enterobacterales in certain regions of the world and are being …

Characterization of Enterobacteriaceae producing OXA-48-like carbapenemases in the UK

V Dimou, H Dhanji, R Pike… - Journal of …, 2012 - academic.oup.com
Objectives To characterize UK clinical isolates of Enterobacteriaceae producing OXA-48-like
carbapenemases and to compare their resistance plasmids. Methods Twenty-six …

OXA-48-like carbapenemases in the UK: an analysis of isolates and cases from 2007 to 2014

J Findlay, KL Hopkins, R Loy, M Doumith… - Journal of …, 2017 - academic.oup.com
Objectives: OXA-48-like carbapenemases have spread worldwide since 2001. We analysed
patient and microbiological data for UK isolates with these enzymes as confirmed by the …

First clinical cases of OXA-48-producing carbapenem-resistant Klebsiella pneumoniae in the United States: the “menace” arrives in the new world

AJ Mathers, KC Hazen, J Carroll, AJ Yeh… - Journal of clinical …, 2013 - Am Soc Microbiol
ABSTRACT OXA-48 has emerged as a major carbapenemase associated with the
Enterobacteriaceae in Europe, North Africa, and Asia. We report the first two clinical cases of …

[HTML][HTML] Phenotypic and genotypic characterization of Enterobacteriaceae producing oxacillinase-48–like carbapenemases, United States

JD Lutgring, W Zhu, TJB de Man, JJ Avillan… - Emerging infectious …, 2018 - ncbi.nlm.nih.gov
Abstract Oxacillinase (OXA)–48–like carbapenemases remain relatively uncommon in the
United States. We performed phenotypic and genotypic characterization of 30 …

OXA-48-like carbapenemases producing Enterobacteriaceae in different niches

A Mairi, A Pantel, A Sotto, JP Lavigne… - European Journal of …, 2018 - Springer
The emergence of carbapenem-resistant enterobacterial species poses a serious threat to
public health worldwide. OXA-48-type carbapenem-hydrolyzing class D β-lactamases are …

Emergence and widespread dissemination of OXA-23, -24/40 and -58 carbapenemases among Acinetobacter spp. in Asia-Pacific nations: report from the SENTRY …

RE Mendes, JM Bell, JD Turnidge… - Journal of …, 2009 - academic.oup.com
Objectives The aim of this study was to evaluate the occurrence and dissemination of
acquired carbapenem-hydrolysing class D β-lactamase (class D carbapenemase)-and …

Laboratory detection and clinical implication of oxacillinase-48 like carbapenemase: the hidden threat

YD Bakthavatchalam, S Anandan… - Journal of global …, 2016 - journals.lww.com
Carbapenemase producing Gram-negative pathogen is of great concern for physician. The
challenging aspects are treatment option and infection control. Monitoring of respective …

OXA-48-like β-lactamases: global epidemiology, treatment options, and development pipeline

SE Boyd, A Holmes, R Peck… - Antimicrobial agents …, 2022 - Am Soc Microbiol
Modern medicine is threatened by the rising tide of antimicrobial resistance, especially
among Gram-negative bacteria, where resistance to β-lactams is most often mediated by β …

Carbapenemase-producing Enterobacteriaceae: overview of a major public health challenge

P Nordmann - Medecine et maladies infectieuses, 2014 - Elsevier
Bacterial resistance to antibiotics has become a major source of concern for public health.
Enterobacteriaceae are among the most common human pathogens, causing community …