Electrically-driven handling of gametes and embryos: taking a step towards the future of ARTs

A Karcz, A Van Soom, K Smits, R Verplancke… - Lab on a Chip, 2022 - pubs.rsc.org
Electrical stimulation of gametes and embryos and on-chip manipulation of microdroplets of
culture medium serve as promising tools for assisted reproductive technologies (ARTs) …

Development of a microfluidic chip powered by EWOD for in vitro manipulation of bovine embryos

A Karcz, A Van Soom, K Smits, S Van Vlierberghe… - Biosensors, 2023 - mdpi.com
Digital microfluidics (DMF) holds great potential for the alleviation of laboratory procedures
in assisted reproductive technologies (ARTs). The electrowetting on dielectric (EWOD) …

Digital microfluidic dynamic culture of mammalian embryos on an electrowetting on dielectric (EWOD) chip

HY Huang, HH Shen, CH Tien, CJ Li, SK Fan, CH Liu… - PloS one, 2015 - journals.plos.org
Current human fertilization in vitro (IVF) bypasses the female oviduct and manually
inseminates, fertilizes and cultivates embryos in a static microdrop containing appropriate …

Fertilization of mouse gametes in vitro using a digital microfluidic system

HY Huang, HH Shen, LY Chung… - IEEE Transactions …, 2015 - ieeexplore.ieee.org
We demonstrated in vitro fertilization (IVF) using a digital microfluidic (DMF) system, so-
called electrowetting on dielectric (EWOD). The DMF device was proved to be biocompatible …

Using a dielectrophoretic microfluidic biochip enhanced fertilization of mouse embryo in vitro

HY Huang, WL Kao, YW Wang, DJ Yao - Micromachines, 2020 - mdpi.com
Droplet microfluidics has appealed to many interests for its capability to epitomize cells in a
microscale environment and it is also a forceful technique for high-throughput single-cell …

Dielectrophoretic oocyte selection chip for in vitro fertilization

W Choi, JS Kim, DH Lee, KK Lee, DB Koo… - Biomedical …, 2008 - Springer
This paper reports a new dielectrophoretic separation method of porcine oocytes for in vitro
fertilization. Conventional manual selection of oocyte highly depends on the expert's …

Microsystems and microfluidic device for single oocyte transportation and trapping: Toward the automation of in vitro fertilising

Z Sadani, B Wacogne, C Pieralli, C Roux… - Sensors and Actuators A …, 2005 - Elsevier
In vitro fertilising (IVF) probably belongs to the most exciting subjects of research, not only for
human assisted reproduction but also for veterinary medicine. Among the various steps of …

Extraction of cell-free Dna from An embryo-culture Medium Using Micro-scale Bio-reagents on ewod

AB Alias, CE Chiang, HY Huang, KT Lin, PJ Lu… - Scientific Reports, 2020 - nature.com
As scientific and technical knowledge advances, research on biomedical micro-
electromechanical systems (bio-MEMS) is also developing towards lab-on-a-chip (LOC) …

A flow through device for simultaneous dielectrophoretic cell trapping and AC electroporation

M Punjiya, HR Nejad, J Mathews, M Levin… - Scientific reports, 2019 - nature.com
Isolation of cells and their transfection in a controlled manner is an integral step in cell
biotechnology. Electric field approaches such as dielectrophoresis (DEP) offers a more …

A medical innovation: A new and improved method of DNA extraction with electrowetting-on-dielectric of genetic testing in-vitro fertilization (IVF)

CE Chiang, HY Huang, KT Lin, AB Alias, PJ Lu… - Microfluidics and …, 2020 - Springer
The current technique for the detection of fetus genotype by in-vitro fertilization (IVF) is quite
expensive and is unsuitable/inconvenient for all patients and even affects the embryonic …