A Yeast under Cover: the Capsule of Cryptococcus neoformans

I Bose, AJ Reese, JJ Ory, G Janbon, TL Doering - Eukaryotic cell, 2003 - Am Soc Microbiol
Few fungi are pathogenic to humans. Of these, Cryptococcus neoformans has emerged as
an important cause of mortality in immunocompromised patients, especially those with AIDS …

Molecular architecture of the Cryptococcus neoformans capsule

MA Gates, P Thorkildson, TR Kozel - Molecular microbiology, 2004 - Wiley Online Library
Many microbes are surrounded by phagocytosis‐inhibiting capsules. We took advantage of
the large size of the polysaccharide capsule of the pathogenic yeast Cryptococcus …

Replication of Cryptococcus neoformans in macrophages is accompanied by phagosomal permeabilization and accumulation of vesicles containing polysaccharide …

SC Tucker, A Casadevall - Proceedings of the National …, 2002 - National Acad Sciences
Cryptococcus neoformans (CN), an encapsulated, ubiquitous environmental yeast, is
pathogenic for humans, primarily those with compromised immune function. CN is believed …

Spatial and temporal sequence of capsule construction in Cryptococcus neoformans

LM Pierini, TL Doering - Molecular microbiology, 2001 - Wiley Online Library
The pathogenic yeast Cryptococcus neoformans is distinguished by an extensive
polysaccharide capsule, which impedes host defences and is absolutely required for fungal …

Cryptococcus neoformans Is a Facultative Intracellular Pathogen in Murine Pulmonary Infection

M Feldmesser, Y Kress, P Novikoff… - Infection and …, 2000 - Am Soc Microbiol
To produce chronic infection, microbial pathogens must escape host immune defenses.
Infection with the human pathogenic fungus Cryptococcus neoformans is typically chronic …

[PDF][PDF] Dismantling the Cryptococcus coat

CA D'Souza, J Heitman - Trends in microbiology, 2001 - Citeseer
Cryptococcus neoformans is an encapsulated yeast and an opportunistic fungal pathogen
responsible for lifethreatening infections of the central nervous system (CNS) in HIV-1 …

The capsule of Cryptococcus neoformans

A Casadevall, C Coelho, RJB Cordero, Q Dragotakes… - Virulence, 2019 - Taylor & Francis
The capsule of Cryptococcus neoformans is its dominant virulence factor and plays a key
role in the biology of this fungus. In this essay, we focus on the capsule as a cellular …

How Sweet it is! Cell Wall Biogenesis and Polysaccharide Capsule Formation in Cryptococcus neoformans

TL Doering - Annual review of microbiology, 2009 - annualreviews.org
Cryptococcus neoformans is a pathogenic fungus responsible for severe opportunistic
infections. The most prominent feature of this yeast is its elaborate polysaccharide capsule …

Dangerous Liaisons: Interactions of Cryptococcus neoformans with Host Phagocytes

EA Gaylord, HL Choy, TL Doering - Pathogens, 2020 - mdpi.com
Cryptococcus neoformans is an opportunistic fungal pathogen and a leading cause of death
in immunocompromised individuals. The interactions of this yeast with host phagocytes are …

Intracellular parasitism of macrophages by Cryptococcus neoformans

M Feldmesser, S Tucker, A Casadevall - Trends in microbiology, 2001 - cell.com
Cryptococcus neoformans, an encapsulated fungal pathogen, causes meningoencephalitis
in immunocompromised patients. Recent in vivo studies have demonstrated that C …